昂丹司琼联合氟哌啶醇预防腹腔镜胆囊切除手术后恶心呕吐被引量：4

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摘要目的探讨昂丹司琼联合小剂量氟哌啶醇对腹腔镜胆囊切除术(LC)后恶心呕吐的预防作用。方法 240例择期行LC患者随机分为两组,Ⅰ组118例,Ⅱ组122例。于麻醉诱导前10 minI,组静脉注射昂丹司琼4 mg,肌内注射0.9%氯化钠注射液2 mL,Ⅱ组静脉注射昂丹司琼4 mg,肌内注射氟哌啶醇2 mg;观察手术后24 h内不良反应、镇静情况及恶心呕吐发生率。结果两组均未出现明显不良反应,两组患者镇静评分0～2分,无过分镇静者(P>0.05)。Ⅱ组24 h内恶心呕吐发生率(17.2%)较I组(28.8%)明显降低(P<0.05)。结论昂丹司琼联合使用小剂量氟哌啶醇较单独使用昂丹司琼对预防LC患者恶心呕吐更有效。

作者谢静刘斌

机构地区长沙市第八医院药剂科长沙市第八医院普通外科

出处《医药导报》 CAS 2011年第12期1598-1599,共2页 Herald of Medicine

关键词昂丹司琼氟哌啶醇腹腔镜胆囊切除术恶心呕吐

分类号 R975.4 [医药卫生—药品] R657.4 [医药卫生—外科学]

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