摘要
目的了解杭州市城乡居民碘营养现况及甲状腺疾病患病情况。方法分别从杭州市城区和农村随机抽取3个调查点,每个调查点随机抽取100户居民,检测其家中食盐盐碘浓度,计算每日盐摄入量;采集尿样及血样,检测尿碘、血清游离三碘甲状腺原氨酸(FT3)、血清游离甲状腺素(FT4)和血清促甲状腺激素(TSH)。结果城区盐碘和每日盐摄入量中位数分别为29.40 mg/kg和6.35 g/d,农村盐碘和每日盐摄入量中位数分别为29.65 mg/kg和8.50 g/d;城区尿碘中位数为120.00μg/L,低于农村的188.73μg/L;城区临床甲减、亚临床甲减、临床甲亢、亚临床甲亢和甲状腺疾病总患病率分别为0.13%、10.13%、0.26%、0.52%和11.04%,农村临床甲减、亚临床甲减、临床甲亢、亚临床甲亢和甲状腺疾病总患病率分别为0.85%、3.12%、0.57%、1.99%和6.52%,城区亚临床甲减、甲状腺疾病总患病率高于农村,亚临床甲亢患病率则低于农村。结论杭州市城乡居民碘营养均处于适宜水平,城区居民尿碘水平低于农村,但亚临床甲减和甲状腺疾病总患病率高于农村。
Objective To investigate the present iodine nutritive conditions and prevalence of thyroid diseases in the population of urban and rural areas of Hangzhou city. Methods Three sampling points were randomly selected from rural and urban areas of Hangzhou, and 100 households were selected randomly in each point. We collected their household salt to test the concentration of salt iodine and calculated their daily salt intake, and also sampled their urine and blood to test urine iodine, FT3, FT4 and TSH. Results In urban area, the median of iodine concentration of salt and daily salt intake were 29.40 mg/kg and 6. 35 g/d ; while 29.65 mg/kg and 8.50 g/d in rural area. The median of urinary iodine concentration was 120.00 μg,/L in urban area which was lower than that of 188.73 μg/L in rural area （ Z = 12. 2094, P 〈 0. 0001 ）. The prevalence of clinical hypothyroidism, subclinical hypothyroidism, clinical hyperthyroidism, subclinical hyperthyroidism and overall thyroid diseases were 0. 13%, 10. 13%, 0. 26%, 0. 52% and 11.04% ; while the prevalence in rural area were 0. 85%, 3. 12%, 0. 57%, 1.99% and 6. 52%. The prevalence of subclinical hypothyroidism and overall thyroid diseases in urban area were higher than that in rural area（ x^3 =28. 6100, P〈0. 0001 ;x^2 =9. 2673, P=0. 0023） ; while the hyperthyroidism was lower than rural （ x^3 = 5. 6990, P= 0. 0171 ）. Conclusion The iodine nutrition in rural and urban areas of Hangzhou city were in a suitable status. The level of urine iodine in urban area was lower than rural area, and the prevalence of subclinical hypothyroidism and thyroid disease was higher than that of rural area.
出处
《浙江预防医学》
2011年第12期13-15,25,共4页
Zhejiang Journal of Preventive Medicine
基金
杭州市科技局科研项目(200908033B27)
