摘要
背景:半月板损伤后较难自我恢复,组织工程学手段为其功能恢复提供了可能。目的:全面综述半月板损伤的治疗方法,着重阐述了半月板的组织工程修复情况。方法:应用计算机检索PubMed和万方数据库中1980-01/2011-03关于半损伤及医用材料的文章,在标题和摘要中以"半月板、治疗、措施、材料"或"meniscus,treatment,the measure,materials"为检索词进行检索。选择研究内容与半月板治疗措施及材料学选择相关的文章,同一领域文献则选择近期发表或发表在权威杂志上的文章。结果与结论:初检得到174篇文献,根据纳入标准选择35篇文章进行综述。研究发现软骨组织周边区域具有一定的自我修复功能,对于规则性裂伤应进行保留组织进行传统疗法治疗,后期效果较好,对于较严重的损伤传统疗法却无能为力,运用组织工程学手段对其进行治疗的材料学条件日趋多元与成熟,理想材料的研制与选择是制约其康复效果的重要因素。
BACKGROUND：The self-restoring ability of meniscus injury is poor.Tissue-engineered methods provide the possibility for the meniscus function recovery.OBJECTIVE：To review the treatment of meniscus injury,and to emphasize tissue-engineered repair of meniscus.METHODS：An online search of PubMed database and Wanfang database was performed using of ＂meniscus,treatment,the measure,materials＂ in both English and Chinese for articles on meniscus injury and its medical materials published between January 1980 to March 2011.Articles related to the treatment and materials of meniscus were retained.Articles published recently or in authoritative journals were of priority.RESULTS AND CONCLUSION：A total of 174 articles were obtained in initial search.According to the inclusion criteria,35 articles were finally selected.Research shows that areas surrounding the cartilage have a certain self-repair ability.It has desirable effects on the later stage of conventional treatments for regularity laceration which preserves the tissue,and has very little influence on the conventional treatments for serious injury.The condition to make use of tissue-engineered methods for meniscus treatment is becoming increasingly diverse and matured.The selection and development of ideal material are important factors of restricting the rehabilitation effect.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2011年第46期8718-8721,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
