摘要
背景:虚拟内窥镜能够充分显示结肠的解剖形态以及病变部位,并从狭窄、梗阻处两端观察肠腔的解剖和病变。结合三维图像还可了解肠壁以及腔外的情况,更有利于肿瘤的定性以及分期诊断。目的:探讨64层CT造影断层图像虚拟技术和64层螺旋CT三维成像与仿真内镜在结肠肿瘤诊断中的应用价值。方法:应用Philips/Brilliance 64 CT对10例术后病理标本证实的结肠癌(8例)和结肠息肉(2例)进行容积扫描。Mimics软件用Marching Cubes算法对肠管进行面绘制及用虚拟内镜法重建三维图像及基于CT造影二维图像对大肠及周围结构等各种组织进行三维重建,并与Brilliance workspace工作站三维成像和仿真内镜结果相比较。结果与结论:10例三维成像效果良好,虚拟内镜与CT仿真内镜显示基本一致。虚拟结肠镜结合多结构数字模型重建可以提供更多信息,有助于病变的准确定位,能准确反映其复杂的解剖结构及空间毗邻关系。说明64层CT造影断层图像虚拟技术能达到与CT仿真内镜结合三维成像同样的敏感性和特异性,加上各种组织三维重建技术可以提供较仿真内镜更丰富的信息。
BACKGROUND：Virtual endoscopy can fully display the anatomy form and pathological changes of the colon at both ends of stenosis and obstruction sites.Combined with three-dimensional（3D） images,we can also understand the conditions of the bowel wall and external cavity,which is more advantageous to the qualitative and stage diagnosis of tumors.OBJECTIVE：To investigate the application value of virtual technology based on 64-slice CT angiography（CTA） images,64-slice CT 3D imaging and virtual endoscopy in the diagnosis of colon tumors.METHODS：Philips/Brilliance 64 CT volumetric scanning was performed in 10 patients with colonic diseases confirmed based on postoperative pathological specimens,including 8 cases of colon tumors and 2 of colonic polypi.Mimics software was used for the surface rendering of the intestine with the Marching Cubes algorithm followed by virtual endoscope 3D reconstruction,and 3D reconstruction of the large intestine and surrounding tissues was done using the Mimics software based on the CTA two-dimensional images.The reconstructed 3D models were compared with 3D images and virtual endoscopy results obtained in the Brilliance workspace.RESULTS AND CONCLUSION：Satisfied results were achieved from 3D images of 10 patients,and there were no significant differences between the findings of virtual endoscopy and CT virtual endoscopy.Virtual colonoscopy combined with multi-structure digital model reconstruction could provide more information,which was helpful to accurately locate the lesion position and could precisely show complex anatomical structures and spatial adjacent relations.Virtual technologies based on 64-slice CTA images nearly have the same sensitivity and specificity as CT virtual endoscopy combined with 3D images.The former one combined with 3D reconstruction techniques in various tissues can provide more information than CT virtual endoscopy.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2011年第48期9023-9026,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
基金
广东省自然科学基金项目(10151051501000026)~~
