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视神经炎的遗传学研究进展 被引量:1

Recent progress on genetics of optic neuritis
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摘要 视神经炎是一种神经眼科的常见疾病,严重威胁视力。目前其病因不明,但研究发现视神经炎伴有一定程度的家族性和遗传倾向。近年来,随着分子生物学技术和统计学方法的迅速发展,视神经炎的候选基因的关联研究取得了相当的进展,本文就目前与视神经炎相关的遗传学研究工作的最新进展加以阐述。 Optic neuritis (ON) is a common disorder of the neuro-ophthalmology, which harms patients vision seriously. However, there are a lot of controversy and confusion about its etiology. While ON has familial characteristic and the tendency of heredity to some extent. Recently, association studies have made considerable progress with the rapid development of molecular biology techniques and statistical methods. In this article, the latest progresses in genetics of ON are reviewed.
出处 《中华眼科杂志》 CAS CSCD 北大核心 2011年第12期1143-1146,共4页 Chinese Journal of Ophthalmology
关键词 视神经炎 脱髓鞘疾病 疾病遗传易患性 Optic neuritis Demyelinating diseases Genetic predisposition to disease
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参考文献40

  • 1Optic Neuritis study Group.The 5 year risk of MS after optic neuritis experience of the optic neuritis treatment trial.Neurology,1997,49:1404-1413.
  • 2张晓君,王薇,王虔,魏文斌,魏永祥.视神经炎病因学临床分析[J].中华眼底病杂志,2006,22(6):367-369. 被引量:58
  • 3Bhatti MT, Schmitt NJ, Beatty RL. Acute inflammatory demyelinating optic neuritis:current concepts in diagnosis and management.Optometry,2005,76:526-535.
  • 4韦企平.视神经炎[J].中国中医眼科杂志,2003,13(3):165-169. 被引量:6
  • 5Begovich AB,Oksenberg JR.Variation in genes regulation the immune system and relationship to disease. Oxford:Taylor and Francis,2000:139-174.
  • 6Kelly MA,Cavan DA,Penny MA,et al.The influence of HLADR and-DQ alleles on progression to multiple sclerosis following a clinically isolated syndrome.Hum Immunol,1993,37:185-191.
  • 7Soderstrom M,Lindqvist M,Hillert J,et al. Optic neuritis:findings on MRI,CSF examination and HLA class Ⅱ typing in 60 patients and results of a short-term follow-up.J Neurol,1994,241:391-397.
  • 8Hillert J,Kadl T,Olerup O,et al.Distribution of HLA-Dw2 in optic neuritis and multiple sclerosis indicates heterogeneity.Acta Neurol Scand,1996,94:161-166.
  • 9Frederiksen JL,Olesen J,Larsson HB,et al. Acute unilateral papillitis versus retro bulbar neuritis:relation to multiple sclerosis.Mult Scler,1996,1:223-227.
  • 10Frederiksen JL,Madsen HO,Ryder LP,et al.HLA typing in acute optic neuritis.Relation to multiple sclerosis and magnetic resonance imaging findings.Arch Neurol,1997,54:76-80.

二级参考文献59

  • 1赖春涛,杨凌,尚军,张晓君,王景群,王薇,秦朝晖,王虔,孙林,余华峰.Leber遗传性视神经病的线粒体基因突变及临床特征[J].中国神经精神疾病杂志,2005,31(1):8-10. 被引量:4
  • 2于逢春,余华锋,孙彦斌,秦朝晖,王锦鹏.以视力损害为首发症状的神经梅毒临床分析[J].眼科,2005,14(6):389-392. 被引量:13
  • 3Volpe N J.Optic Neuritis: Historical Aspects[J] .J Neuro- Oph-thalmol,2001,21(4):302 -- 309.
  • 4Beck R W, Cleary P A, Anderson M M.Optic Neuritis Study Group.A randomized,cantrolled trial of corticosteroids in the treatment of acute optic neuritis[J] .N Engl J Med, 1992,326:581 - 588.
  • 5Trobe J D, Sieving P C, Guire K E, et al. The impact of the optic neuritis treatment trial on the practices of ophthalmologists arid neurologist[J]. Ophthalmology, 1999,106:2047 - 2053.
  • 6Eggenberger E R. Inflammatory optic neuropathies[J]. Ophthalmology Clinics of North America,2001, (14)1:73- 82.
  • 7Miller N R, Newman N J, Walsh, et al. Clinical neuro- ophthalmology: Optic neuritis[ M]. 5th ed. Baltimore: Williams & Wilking,1999.196 - 220.
  • 8Hwang J M, Lee Y J, Kim M K.Statistics of optic neurophthy in seoul municipal boramae hospital in korea[J] .Neuro Ophthalmol,2000,24(4) :489 - 495.
  • 9Kanski J J. Clinical Ophthalmology[M] .4th ed. Oxford: Butterworth- Heinemann, 2000.590 - 593.
  • 10Rao N A.Chronic experimental allergic optic neuritis[J] .Invest Ophthalmol, 1981,20:159 - 172.

共引文献64

同被引文献41

  • 1张晓君,王薇,王虔,魏文斌,魏永祥.视神经炎病因学临床分析[J].中华眼底病杂志,2006,22(6):367-369. 被引量:58
  • 2Toosy AT, Mason DF, Miller DH. Optic neuritis[J]. Lancet Neurol, 2014, 13(1): 83-99.
  • 3Pau D, A1 Zubidi N, Yalamanchili S, et al. Optic neuritis[J]. Eye, 2011, 25(7): 833-842.
  • 4Miller NR, Newman N J, Biousse V, et al. Walsh and Hoyt's clinical neuro-ophthalmology[M]. 6th eds. Baltimore: Lippincott Williams&Wilkins, 2005: 293-326.
  • 5Balcer LJ. Optic neuritis[J]. N Engl J Med, 2006, 354(12): 1273-1280.
  • 6Suehiro S, Adachi-Usami E, Miyauchi O, et al. Clinical profiles of patients with optic neuritis at the Ophthalmological Department of Chiba University[J]. Neuro- Ophthalmology, 2009, 27(1-3): 153-162.
  • 7Wakakura M, Minei-Higa R, Oono S, et al. Baseline features of idiopathic optic neuritis as determined by a muhieenter treatment trial in Japan[J]. Jpn J Ophthalmol, 1999, 43(2): 127-132.
  • 8Lucas RM, Ponsonby AL, Dear K, et al. Sun exposure and vitamin D are independent risk factors for CNS demyeliuation [J]. Neurology, 2011, 76(6): 540-548.
  • 9Cristiano E, Patrucco L, Rojas JI. A systematic review of the epidemiology of multiple sclerosis in South America[J]. Eur J Neurol, 2008, 15(12): 1273-1278.
  • 10Rodriguez M, Siva A, Cross SA, et al. Optic neuritis: a population-based study in Olmsted County, Minnesota[J]. Neurology, 1995, 45(2): 244-250.

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