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重度烧伤患者肠内早期营养支持的临床研究 被引量:5

Effects of early enteral nutrition on severly burned patients
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摘要 目的探讨早期肠内营养在重度烧伤患者治疗中的应用价值。方法选择56例重度烧伤患者,随机分为两组,观察组给予早期肠内营养支持,对照组给予肠外营养,比较两组治疗前后生化指标及氮平衡时间、创面愈合时间以及并发症发生率。结果治疗后观察组白蛋白变化不显著,而对照组较治疗前下降明显(P<0.05);观察组前白蛋白、转铁蛋白水平显著高于对照组,C反应蛋白、TNF-α水平显著低于对照组(P<0.05);观察组氮平衡及创面愈合时间明显短于对照组(P<0.05);观察组消化道不良发生率高于对照组,但消化道出血及全身感染发生率均低于对照组(P<0.05)。结论肠内营养支持可以降低烧伤患者高代谢反应、改善营养状况,提高治疗效果、降低并发症发生率。 Objective To evaluate the effects of early enteral nutrition on severely burned patients. Methods 56 severely burned pa- tients were randomly divided into two groups, the observation group were given early enteral nutrition and the control group were given parenteral nutrition. The biochemical parameter levels, nitrogen balance time, wound healing time and complication rate were compared. Results After treatment, the level of Alb in observation group were not changed, while that in the control group were significantly decreased ( P 〈 0.05 ). The levels of PALB ,Trf in the observation group were significantly higher, while the CRP, TNF -α were significantly lower than that in the control group( P 〈 0. 05 ). The nitrogen balance and wound healing time in the observation group were significantly shorter than that in the control group (P 〈0. 05) ;The gastrointestinal adverse rate in the observation group was higher, but gastrointestinal bleeding and systemic infection rate was lower than that in the control group ( P 〈 0.05 ). Conclusion Enteral nutrition can reduce the high metabolic response in burn patients and im- prove the nutritional status and effects of treatment and reduce the complications rate.
出处 《中外医学研究》 2011年第35期12-13,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 烧伤 营养支持 氮平衡 Burn Nutritional support Nitrogen balance
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