摘要
目的:探讨糖尿病母亲婴儿血脂情况。方法:对北京大学人民医院2005年1月～2010年12月收治的63例糖尿病母亲婴儿的相关资料进行回顾性分析,比较糖尿病母亲婴儿与正常新生儿血脂情况有无差异,并分析其血脂与出生体重、胎龄、性别及母亲血糖控制情况的相关性。结果:与正常新生儿相比,糖尿病母亲婴儿血胆固醇〔(2.50±0.91)vs(1.76±0.47)mmol/L〕、甘油三酯〔(0.70±0.50)vs(0.38±0.17)mmol/L〕、高密度脂蛋白〔(0.73±0.23)vs(0.51±0.14)mmol/L〕、低密度脂蛋白〔(1.23±0.62)vs(0.78±0.40)mmol/L〕均增高,差异有显著性。与早产糖尿病母亲婴儿相比,足月产糖尿病母亲婴儿血甘油三酯〔(1.04±0.58)vs(0.48±0.34)mmol/L〕增高,高密度脂蛋白〔(0.64±0.17)vs(0.78±0.24)mmol/L〕降低,差异有显著性。与适于胎龄糖尿病母亲婴儿相比,大于胎龄糖尿病母亲婴儿血脂无差异。与母亲血糖控制良好组相比,母亲血糖控制欠佳组婴儿血脂无显著差异。与糖尿病母亲男性婴儿相比,糖尿病母亲女性婴儿血脂亦无统计学差异。糖尿病母亲婴儿血甘油三酯与出生体重、胎龄呈正相关,血高密度脂蛋白与出生体重、胎龄呈负相关,血胆固醇及低密度脂蛋白与出生体重、胎龄无相关性。结论:糖尿病母亲婴儿的血脂水平较正常新生儿增高,其中足月者较早产者血甘油三酯增高,高密度脂蛋白减低。糖尿病母亲婴儿血甘油三酯与体重、胎龄呈正相关,高密度脂蛋白与体重、胎龄呈负相关。
Objective：To explore the blood lipids levels of infants born by mothers with diabetes mellitus. Methods：The related data of 63 infants born by mothers with diabetes mellitus who were treated in the hospital from January 2005 to December 2010 were analyzed retrospectively.The blood lipids levels of infants born by mothers with diabetes mellitus and normal neonates were compared,the correlation between blood lipids,birth weight,fetal age,gender and controlling situation of maternal glucose was analyzed. Results：The blood levels of cholesterol,triglyceride,high density lipoprotein and low density lipoprotein in diabetes group were（2.50±0.91） mmol/L,（0.70±0.50） mmol/L,（0.73±0.23） mmol/L and（1.23±0.62） mmol/L,respectively,which were significantly higher than those in normal group（（1.76±0.47） mmol/L,（0.38±0.17） mmol/L,（0.51±0.14） mmol/L and（0.78±0.40） mmol/L,respectively）.In diabetes group,compared with the premature infants,the blood triglyceride level of full-term infants increased（（1.04±0.58） mmol/L vs.（0.48±0.34） mmol/L）,the blood high density lipoprotein level decreased（（0.64±0.17） mmol/L vs.（0.78±0.24） mmol/L）,there was significant difference.There was no significant difference in blood lipids levels between appropriate for gestational age infants and large for gestational age infants.There was no significant difference in blood lipids levels between the infants born by mothers with well-controlled glucose and the infants born by mothers with bad-controlled glucose.There was no significant difference in blood lipids levels between female infants and male infants.In diabetes group,there was a positive correlation between blood triglyceride level and birth weight and fetal age of infants,and there was a negative correlation between blood high density lipoprotein level and birth weight and fetal age of infants;there was no correlation between blood cholesterol and low density lipoprotein levels and birth weight and fetal age of infants. Conclusion：The blood lipids levels of infants born by mothers with diabetes mellitus are higher than those of normal neonates,compared with premature infants,the blood triglyceride level of full-term infants increases,while blood high density lipoprotein level decreases.Among the infants born by mothers with diabetes mellitus,there is a positive correlation between triglyceride level and birth weight and fetal age of infants,high density lipoprotein is negatively correlated with birth weight and fetal age of infants.
出处
《中国妇幼保健》
CAS
北大核心
2011年第35期5523-5525,共3页
Maternal and Child Health Care of China
关键词
糖尿病母亲婴儿
胆固醇
甘油三酯
高密度脂蛋白
低密度脂蛋白
Infants born by mothers with diabetes mellitus
Cholesterol
Triglyceride
High density lipoprotein
Low density lipoprotein
