摘要
目的分析HIV-1抗体阳性吸毒者的WB带型,了解惠州市男性吸毒人群WB带型的分布特征。方法对本实验室2007～2010年的HIV-1抗体确证检测阳性男性吸毒者的WB带型进行统计分析。结果 113份HIV-1抗体确证检测阳性男性吸毒者的WB带型中,gp160、gp120带型的出现率均在100%,p66、p51、gp41、p31、p24带型的出现率均在96%以上,p55,p17带型的出现率分别为71.68%和80.53%;WB全带型出现率为59.30%(67/113);不同年龄组带型差异无统计学意义。结论抗env和gag基因编码蛋白的抗体gp160、gp120、gp41、p24阳性率高,是确证HIV-1感染的必备条件;惠州市的HIV亚型、传播途径和WB带型之间的关系有待进一步的调查和研究。
Objective To understand the distribution of western blot（WB） bands of male drug addicts infected with HIV-1 virus in Huizhou City.Methods All the HIV-1 antibody positive samples of drug addicts from 2007 to 2010 in our laboratory were collected and the WB bands were analyzed.Results Among the 113 samples,gp160,gp120 were expressed in 100% of the samples,p66,p51,gp41,p31,p24 band were expressed in over 96% of the samples;p55,p17 was expressed in 71.68% of the samples and 80.53% samples;the percentage of the samples expressed all bands was 59.30%（67/113）.The expression of different WB bands showed no significant difference among different age groups.Conclusion The positive rates of gp160,gp120,gp41,p24,which were encoded by env and gag gene,were high.It was the prerequisite for confirmation of HIV-1 virus infection.The relationship among WB band,HIV-1 gene subtype,and route of transmission needs to be further investiaged.
出处
《中国热带医学》
CAS
2011年第11期1330-1331,共2页
China Tropical Medicine
