摘要
肺部感染与非感染性肺部炎症性疾病是临床常见的疾病。由于二者在临床及影像学方面具有一定的相似性，常常导致抗生素的延误使用或过度使用。sTREM-1是新近发现的重要炎症标志物，作为专一表达于中性粒细胞、单核／巨噬细胞表面的跨膜糖蛋白，sTREM-1有望成为肺部感染早期诊断的指标，从而起到指导抗生素使用的作用。本文就sTREM-1与肺部感染的关系作一综述。
Pulmonary infectious diseases and non-infectious pulmonary inflammatory diseases are clinically common diseases. These diseases may present some similar clinical and radiotogical features, which often lead to the antibiotics administered delayed or excessively. Soluble triggering receptor expressed on myeloid cell-1 （sTREM-1）, expressing singly on the surface of neutrophils and monocytes/ macrophage, is an recently found important inflammation marker which might be an early diagnosis marker and be helpful for antibiotics administration in pulmonary infectious diseases. The updates of studies on the relationship between sTREM-1 and pulmonary infectious diseases are reviewed in this article.
出处
《国际呼吸杂志》
2011年第24期1886-1890,共5页
International Journal of Respiration
基金
甘肃省自然基金项目（1010RJZA051）
