摘要
目的:分析脾切除加自体脾移植治疗肝硬化脾大的临床疗效。方法:检测我院采取脾切除加自体脾移植治疗的肝硬化脾大患者术前、术后肝功能及血常规,并进行对比,同时将术后2年回访的谷丙转氨酶(ALT)复常情况同术前进行对比。结果:术后2年ALT>80 U/L的患者占比由术前的76.79%下降为19.64%;腹水患者占比由术前的87.50%下降为16.07%;肝萎缩患者占比由术前的60.71%下降为33.93%,术后患者病情得到显著改善(P<0.01)。结论:脾切除加自体脾移植有效地保存了自体脾片组织,提高了患者术后机体免疫功能,使肝硬化致脾大患者术后的肝功能得到了良好改善。
Objective：To analyze the clinical effect of splenectomy and splenic autotransplantation in the treatment of hepatocirrhosis splenomegaly.Methods：The liver function and conventional blood were detected before and after surgery of hepatocirrhosis splenomegaly patients taking the treatment of splenectomy and splenic autotransplantation in our hospital,and did comparison,the situation of alanine aminotransferase（ALT） normalization was compared while a return visit after two years with preoperative.Results：After two years,ALT〉80 U/L proportion of patients decreased from 76.79% before surgery to 19.64%;proportion of patients with ascites decreased from 87.50% before surgery to 16.07%;proportion of patients with liver atrophy decreased from 60.71% before surgery to 33.93%,the patient＇s condition improved significantly after surgery（P〈0.01）.Conclusion：Splenectomy and splenic autotransplantation effectively preserve autologous splenic tissue,improve the postoperative immune function of patients,and the liver function of the patients with hepatocirrhosis caused by splenomegaly are improved well.
出处
《中国医药导报》
CAS
2011年第36期170-171,共2页
China Medical Herald
关键词
肝硬化
脾功能亢进
脾肿大
脾切除
自体脾移植
Hepatocirrhosis
Hypersplenism
Splenomegaly
Splenectomy
Splenic autotransplantation
