摘要
目的 探讨糖尿病中医证型与糖尿病视网膜病变分期之间的关系。方法 1 85例(2 83只眼 )糖尿病患者包括未发生糖尿病视网膜病变者 90只眼和发生糖尿病视网膜病变者 1 93只眼。按照中医辨证分型其中气阴两虚型 2 0 0只眼 ,阴阳两虚型 3 7只眼 ,血瘀气滞型 46只眼。根据糖尿病视网膜病变的分期 ,1 93只视网膜病变眼中有单纯型糖尿病视网膜病变 5 0只眼 ,增殖前期 64只眼 ,增殖期 79只眼。分别与病程、发病率、视力及中医证型进行了分析。结果 在发生糖尿病视网膜病变的患者中病程 5年以下者多为气阴两虚证 ;病程 5～ 1 0年者多为血瘀气滞证 ;病程 1 0年以上者多为阴阳两虚证。血瘀气滞组、气阴两虚组与阴阳两虚组在糖尿病患者中构成比之间差异均有非常显著性 (P <0 0 1 )。糖尿病视网膜病变分期与中医证型的构成比差异有非常显著性 (P <0 0 1 )。结论 糖尿病患者中阴阳两虚证和血瘀气滞证者发生视网膜病变明显高于气阴两虚证 ,并与病程有一定关系。单纯期和增殖前期病变中多为气阴两虚证 ;增殖期则多为血瘀气滞证和阴阳两虚证。血瘀气滞证糖尿病视网膜病变患者的视力损害较为严重。
OBJECTIVE To investigate a relationship between traditional Chinese medicine ( TCM ) syndrome types of diabetes mellitus ( DM ) and stages of diabetic retinopathy ( DR ). METHODS One hundred and eighty five patients (283 eyes) with DM were observed, including 90 eyes without DR and 193 eyes with DR. The patients were classified as 200 eyes of qiyinliangxu (气阴两虚), 37 eyes of yinyangliangxu (阴阳两虚), and 46 eyes xeyuqizhi (血瘀气滞) according to TCM syndrome types. There were 50 eyes with background stage, 64 eyes with pre proliferative stage, and 79 eyes with proliferative stage in 193 eyes with DR based on stages of DR. Course of disease, ratio of DR stage, visual acuity and TCM syndrome types were analyzed. RESULTS In patients whose course of DR were no more than 5 years qiyinliangxu types comprised most part of patients, xeyuqizhi types comprised most part of patients with 5 to 10 years of DR. Over 10 years there were more yinyangliangxu types. Ratio of DR in DM of xieyuqizhi types, qiyinliangxu types of DR and yinyangliangxu types had a significant difference between them ( P <0 01 ). The ratio of stages of DR and TCM syndrome types had a significant difference ( P <0 01) in the patients.CONCLUSION Incidence of retinopathy is higher obviously in the patients with diabetes mellitus as yinyangliangxu and xeyuqizhi than qiyinliangxu, and it is relevant with the courses of disease. There were more qiyinliangxu in the patients with background and pre prolifrative retinopathy, but more xeyuqizhi and yinyangliangxu in the proliferative retionpathy. Loss of visual acuity is more severe in the patients with diabetic retinopathy as xeyuqizhi type.
出处
《中国中医眼科杂志》
2000年第1期29-32,共4页
China Journal of Chinese Ophthalmology
基金
卫生部科学基金!编号 96 - 2 - 2 0 82
广东省科学技术委员会科学基金!编号 97- 2 - 4
关键词
糖尿病
视网膜病变
中医证型
中医药疗法
diabetes mellitus retinopathy traditional Chinese medicine syndrome types
