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消化道恶性肿瘤患者CA19-9、CEA联合检测的价值及意义 被引量:12

VALUE AND SIGNIFICANCE OF CA19-9 AND CEA IN SERUM OF PATIENTS WITH GASTRO-INTESTINAL CANCER
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摘要 目的:通过对外周血CA19-9、CEA的联合检测,了解其对消化道恶性肿瘤诊断的价值及临床意义。方法:采用酶联免疫吸附法对128例消化道恶性肿瘤患者的CA19-9、CEA水平进行测定。结果:肿瘤组CA19-9水平显著高于正常对照组(P<0.05),阳性率:结/直肠癌组16.6%,胃/贲门癌组13.3%。肿瘤组CEA水平显著高于正常对照组(P<0.001)。阳性率:结/直肠癌组52.4%,胃/贲门癌组38.6%。结论:CA19-9和CEA的联合检测,可提高消化道肿瘤诊断的特异性,并对疗效观察、监测肿瘤的转移与复发有实际意义。 Objective:To evaluate the diagnostic value and the clinical significance for measuring the serum levels of CA19 9 and CEA in gastro intestinal cancer.Methods:The serum levels of CA19 9 and CEA were determined in 128 cases with gastro intestinal cancer by enzyme immunometric assay.Results:In cancer patients, the CA19 9 levels were markedly elevated (P<0.05),the positive rate was 16.7% in colorectal cancer and 13.3% in carcinoma ventriculi and cardiac cancer.The CEA levels were markedly elevated (P<0.001).The positive rate was 52.4% in colorectal cancer and 38.6% in carcinoma ventriculi and cardiac cancer. The positive rate was 52.4% in colorectal cancer and 38.6% in carcinoma ventriculi and cardiac cancer. Conclusion:The examination of CA19 9 and CEA can elevate the specificity of diagnosis of gastro intestinal cancer,and have positive value for detecting the treatment effect and metastasis.
机构地区 山西省肿瘤医院
出处 《肿瘤研究与临床》 CAS 2000年第1期17-18,共2页 Cancer Research and Clinic
关键词 肿瘤标记物 酶联免疫试验 消化道肿瘤 Tumor marker Enzyme immunometric assay
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  • 1齐为民,国外医学临床生物化学与检验学分册,1994年,15卷,2期,56页

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