1Lauer,G.M.& Walker,B.D.,Hepatitis C virus infection[J].N Engl J Med,2001,345,41.
2Global surveillance and control of hepatitis C.Report of a WHO Consultation organized in collaboration with the Viral Hepatitis Prevention Board,Antwerp,Belgium[J].J Viral Hepat,1999,6(1),35.
3P.Simmonds,E.C.Holmes,T.A.cha,et al.Classification of hepatitis C virus into six major genotypes and a series of subtypes by phylogenetic analysis of the NS-5 region[J].J Gen Virol,1993,74(11):2391.
5Manns,M.P.et al.Peginterferon alfa-2a plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C:a randomized trial[J].Lancet,2001,358:958.
6Fried,M.W.et al.Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection[J].N.Engl.J.Med,2002,347:975.
7Hadziyannis,S.J.et al.Peginterferon-alpha 2a and ribavirin combination therapy in chronic hepatitis C:a randomized controlled trial.J.Hepatol[J].2004,41:474.
8Fried,M.W.Side effects of therapy of hepatitis C and their management.[J] ,Hepatology,2002,36:S237.
4[1]Lewontin RC:The interaction of selection and linkage.I.general considerations:heterotic models.Genetics1964,49:49~67
5[2]Pritchard JK,Przeworski M.Linkage disequilibrium in humans:models and data.Am J Hum Genet2001,69:1~14
6[3]Remington DL,Thomsberry JM,Matsuoka Y,Wilson LM,Whitt SR,Doebley J,Kresovich S,Goodman MM,Buckler ES:Structure of linkage disequilibrium and phenotypic association in the maize genome.Proc Natl Acad Sci USA2001,98:11479~11484
7[4]Reich DE,Cargill M,Bolk S,Ireland J,Sabeti PC,Richter DJ,Lavery T,Kouyoumjian R,Farhadian SF,Ward R,Lander ES:Linkage disequilibrium in the human genome.Nature2001,411:199~204
8[5]Moffatt MF,Traherne JA,Abecasis GR,Cookson WOCM:Single nucleotide polymorphisms and linkage disequilibrium within the TCR α/δ locus.Hum.Mol.Genet2000,9:1011~1019