摘要糖尿病肾病是糖尿病最严重的并发症之一,是美国、日本等发达国家终末期肾病的主要原因。目前,糖尿病肾病具体发病机制尚不明确,既往研究主要集中在高血糖及其糖基化终末产物（advancedglycation end products,AGEs）的形成,脂代谢紊乱及血流动力学异常等，近年来许多动物实验和临床研究均表明糖尿病。肾病往往存在着炎症介质的表达增高。我们对糖尿病肾病炎症机制及抗炎治疗进行探讨。
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