期刊文献+

自拟壮心汤对心力衰竭患者心肌重塑的改善效果 被引量:2

下载PDF
导出
摘要 慢性充血性心力衰竭(CHF),是多种病因所致心脏病的终末阶段。目前已明确,导致心力衰竭发生发展的基本机制是心肌重塑,主要表现在心肌质量、心室容量的增加和心脏形状的改变(横径增加呈球状)。因此,心力衰竭的治疗目标不仅仅是改善症状、提高生活质量.更重要的是防止和延缓心肌重塑的发展,注重远期效果,降低住院率及病死率。
出处 《实用医药杂志》 2012年第1期37-38,共2页 Practical Journal of Medicine & Pharmacy
  • 相关文献

参考文献3

二级参考文献6

  • 1中华人民共和国卫生部.中药新药临床研究指导原则[s].第1辑.北京:中国科技出版社.1993.57.
  • 2Goldhaber JI, Kin KH, Natterson PD, et al. Effect of TNF-aon [Ca^2+] i and contractility in solated adult rabbit ventricular my- ocytes[J]. AM J Physiol, 1996,271(4):1449-1455.
  • 3Yakiyma T, Nakani M, Bednarczyk JL, et al. Tumor necrosis factor-a provokex: a hypertrophic growth response in adult car- diac myocytes[J]. Circulation, 1997,95(5):1247-1252.
  • 4Bozkurt B, Knrubbs SB, Clubb FJ, et al. Pathophysiologically relevant concentration of tumor necrosis factor promote progre- ssive left ventricular dysfunction and remolding in rats[J]. Cir- culation, 1998,97(14):1382-1391.
  • 5杨丽霞.细胞因子网络与心力衰竭研究进展[J].心血管病学进展,2002,23(1):16-19. 被引量:17
  • 6李晓辉,唐汝愚.丹参酮抑制嗜中性白细胞功能与其防治心肌梗死作用的关系[J].中国药理学报,1991,12(3):269-272. 被引量:23

共引文献112

同被引文献35

  • 1直接接触药品的包装材料和容器管理办法[J].中华人民共和国国务院公报,2005(16):44-48. 被引量:2
  • 2朱奔奔,郭维,黄亮,杨涓,邓兴学.真武汤对慢性充血性心力衰竭模型大鼠ET、CGRP水平的影响[J].江苏中医药,2005,26(8):49-51. 被引量:35
  • 3WilsonI S M. Molecular and cellular mechanisms of myocardial failure[J]. The American Journal of Cardiology, 1997, 80( 11 ) : 15-25.
  • 4Sen S, Kundu G, Mekhail N, et al. Myotrophin: purification of a novel peptide from spontaneously hypertensive rat heart that influ- ences myocardial growth[J]. Journal of Biological Cherrfistry, 1990,265(27) : 16635-16643.
  • 5Purcell N H, Molkentin J D. Is nuclear factor kappaB an attractive therapeutic target for treating cardiac hypem-ophy[ J]. Circulation, 2003,108(6) :638-640.
  • 6Pai J K, Pischon T,Eta M J.1 inflammatorymarkers and the risk of cor-onary heartdisease in men and women[J]. The New England Journal of Medicine, 2004,351 (25) : 2599.
  • 7Liu Yi-nan, Pan S L, Liao C H, et al. Evodiamine represses hypox- ia-induced inflammatory proteins expression and hypoxia-inducible factor lalpha accumulation in RAW264.7[J]. Shock, 2009, 32 (3) :263-269.
  • 8Gonzalez A, Eopez B, Diez J. Fibrosis in hypertensive heart dis- ease: role of the renin-angiotensin-aldosterone system [J]. The Medical Clinics of North America, 2004,88 ( 1 ) : 83-97.
  • 9Stessel H, Brunner F. Effect of endothelin antagonism on contrac- tility, intracellular Calcium regulation and Calcium regulatory protein expression in right ventricular hypertrophy of the rat[ J]. Basic & Clinical Pharmacology & Toxicology, 2004,94 ( 1 ) : 37- 45.
  • 10Aukrust P, Ueland T, Lien , et al. Cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated car- diomyopathy[J]. The American Journal of Cardiology, 1999,83 (3) :376-382.

引证文献2

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部