摘要
目的探讨改良Sugiura手术加脾切除后部分自体脾移植治疗门静脉高压症的临床疗效。方法 2008年5月至2011年5月行择期手术的门静脉高压症患者80例随机分为观察组和对照组各40例,观察组采用改良Sugiura手术加自体脾移植治疗门静脉高压症,对照组采用传统的脾切除加贲门周围血管离断术。比较两组病人术后食管静脉曲张改善情况、再出血等并发症情况及血清Tuftsin和IgM的指标变化情况。结果观察组病人手术后食管胃底静脉曲张改善情况、血清免疫指标Tuftsin和IgM的变化及再出血和并发症情况优于对照组,两组比较有显著性差异(P<0.05)。结论改良Sugiura手术加自体脾移植手术临床效果好、并发症少且保留了脾脏的免疫功能,是一种值得推广的手术方法。
Objective To investigate the clinical efficacy of modified Sugiura surgery plus some splenectomy with autologous spleen transplantation in the treatment of portal hypertension.Methods From May 2008 to June 2011 in our hospital for elective surgery of portal hypertension in 80 patients were randomly divided into two groups and the control group each 40 cases,the observation group modified Sugiura procedure and autologous spleen transplantation in the treatment of portal hypertension the control group using traditional splenectomy plus cardiac peripheral vascular amputation surgery.Compared two groups of patients after variceal improve the situation,re-bleeding and other complications and serum indicators of Tuftsin and IgM changes.Results The patients with esophageal varices after surgery to improve the situation,and IgM in serum immune parameters Tuftsin changes and re-bleeding and complications than the control group,two groups had significant difference（P0.05）.Conclusions The modified Sugiura procedure and autologous spleen transplantation have good clinical results and few complications,and retained the spleen of immune function,is a surgical method should be promoted.
出处
《医药论坛杂志》
2011年第22期3-5,共3页
Journal of Medical Forum
关键词
门静脉高压症
改良SUGIURA术
肝硬化
Portal hypertension
Modified Sugiura procedure
Cirrhosis of the liver
