摘要
[目的]观察抵挡汤对2型糖尿病患者血管内皮功能影响。[方法]选择2型糖尿病患者,观察抵挡汤对血管内皮功能及血清内皮素-1(ET-1)、血清一氧化氮(NO)的影响。[结果]抵当汤组肱动脉舒张率明显增加,血清ET-1水平下降,NO表达上调。[结论]抵当汤对2型糖尿病患者血管内皮功能具有较好的干预作用。
[Objective] To observe the effect of Didang decoction on endothelial function in patients with type 2 diabetes. [Methods] We selected type 2 diabetes patients in my hospital from Jan to Dec of 2009. Endothelium-dependent dilation （FMD and inner diameter of brachial） and blood concentrations of endothelium-related factors （NO, ET-1） were measured before and after treatment. [Results] After treatment, both FMI） and serum concentrations of NO were significantly increased in Didang decoction group, while plasma concentrations of ET-I were decreased. [Conclusion] Didang decoction can improve endothelium function in patients with type 2 diabetes, and its possible mechanisms may be involved in regulating endothelium-related factors.
出处
《天津中医药》
CAS
2011年第6期457-458,共2页
Tianjin Journal of Traditional Chinese Medicine
基金
国家自然科学基金资助项目(30973753)
关键词
抵挡汤
2型糖尿病
血管内皮功能
Didang decoction
type 2 diabetes
endothelium function
