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CT双期扫描对节段性自身免疫性胰腺炎与胰腺癌及胰内分泌肿瘤的鉴别诊断价值 被引量:7

Differentiating segmental autoimmune pancreatitis from pancreatic carcinoma and pancreatic endocrine tumors on the basis of enhancement characteristics at dual-phase CT
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摘要 目的:研究节段性自身免疫性胰腺炎(Autoimmune pancreatitis,AIP)CT双期扫描的强化模式与胰腺癌及内分泌肿瘤(Pancreatic endocrine tumor,PECT)的差异,提高AIP的诊断水平。方法:收集9例节段性AIP患者、25例胰腺癌及16例PECT患者的CT平扫和双期动态增强资料以及25例性别、年龄与AIP相似的正常对照组,分析双期扫描3种病变的影像特点以及与正常胰腺的密度差异;测量4组的双期扫描平均CT值,分别比较AIP组与胰腺癌、PECT组的平均CT值差异,同时与正常对照组比较。结果:动脉期,在图像上,与同病例正常胰腺比较,9例AIP患者的病变胰腺均表现为相对低密度,25例胰腺癌患者呈明显低密度,16例PECT患者均呈高密度;AIP组、胰腺癌组、PECT组的平均CT值分别为72.7HU、49.2HU、115.6HU,正常组的平均CT值为93.4HU。门脉期,在图像上,与同病例正常胰腺比较,9例AIP患者的病变胰腺均为等或偏高密度,25例胰腺癌患者的病变胰腺均为明显低密度;16例PECT患者呈偏高密度;AIP组、胰腺癌组、PECT组的平均CT值分别为86.6HU、57.6HU、104.2HU,正常组的平均CT值为83.9HU。结论:AIP与胰腺癌、PECT的强化模式不同,不同时相,病变与正常胰腺的对比度不同,CT双期扫描在节段性AIP与胰腺癌、PECT鉴别诊断中有重要价值,通过CT双期扫描可作出AIP的倾向性诊断。 Objective: The purposes of this study was to investigate the difference of segmental autoimmune pancreatitis (AIP) from pancreatic carcinoma and pancreatic endocrine tumors (PECT) at dual-phase CT, and to improve the level of diagnosing AIP. Methods: Dual-phase CT scans of 75 patients (9 with segmental autoimmune pancreatitis, 25 with pancreatic carcinoma, 16 with pancreatic endocrine tumors, and 25 with a normal pancreas) were analyzed. Analyze the image findings including the uniformity of density, the shape of lesion, and the contrast density of masses to normal pancreatic parenchyma. The CT attenuation value of the pancreatic parenchyma and pancreatic masses were measured on plain scanning and on arterial-and portal venous phases. Compare the mean CT attenuation value of AlP to pancreatic carcinoma and PECT respectively, all of which were compared with normal pancreas. Results: In the arterial phase, all AIP manifested as hypodense to uninvolved pancreas, and all pancreatic carcinoma manifesed significantly hypodense to normal pancreas, and all PECT manifested hyperdense to normal pancreas; the mean CT attenuation values of AIP, pancreatic carcinoma, PECT and control group were 72.7HU, 49.2HU, llS.6HU and 93.4HU respectively. In the portal venous phase, all AIP manifested slightly hyperdense to uninvolved pancreas, and all pancreatic carcinoma manifesed significantly hypodense to normal pancreas, and all PECT manifested hyperdense to nm^lal pancreas; the mean CT attenuation values of AlP, pancreatic carcinoma, PECT and control group were 86.6HU, 57.6HU, 104.2HU and 83.9HU respectively. Conclusion: At dual-phase CT, the enhancement patterns of AIP was different fi'om that of the pancreatic carcinoma, the pancreatic endocrine tumor and normal pancreas. Dual-phase CT scanning played an important role in differentiating AlP from pancreatic carcinoma and pancreatic endocrine tumors.
出处 《中国临床医学影像杂志》 CAS 北大核心 2011年第12期852-857,共6页 Journal of China Clinic Medical Imaging
关键词 胰腺炎 胰腺肿瘤 体层摄影术 螺旋计算机 Pancreatitis Pancreatic neoplasms Tomography, spiral computed
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