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SCI患者hs-CRP水平和颈动脉粥样硬化的关系

Relationship between serum high-sensitivity C-reactive protein level and carotid atherosclerosis in patients with silent cerebral infarction
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摘要 目的:探讨无症状性脑梗死(SCI)患者血清高敏C反应蛋白(hs-CRP)水平与颈动脉粥样硬化的关系。方法:用免疫散射比浊法测定68例SCI患者和65例健康人血清hs-CRP水平,并对68例SCI患者进行颈动脉彩色多普勒超声检测。结果:SCI血清hs-CRP水平([16.4±4.5)mg/L]高于对照组([10.6±2.7)mg/L(,P<0.01)]。SCI组hs-CRP水平与颈动脉粥样硬化程度(r=0.48,P<0.01)和颈动脉狭窄程度(r=0.51,P<0.05)呈正相关。结论:SCI患者hs-CRP水平与颈动脉粥样硬化有关。 Objective: To investigate the relationship between serum high-sensitivity C-reactive protein level(hs-CRP) and carocid atherosderosis in patients with silent cerebral infarction(SCI). Methods: The serum hs-CRP levels were measured by immunodiffusion turbidimetry in 68 patients with SCI and 65 healthy controls.Color ultrasonography was used to observe the carotid atherosclerosis and the severity of stenosis of the extracranial carotid in 68 patients with SCI. Results: The serum hs-CRP level in SCI group[(16.4±4.5)mg/L] was significantly higher than that in control group[(10.6±2.7)mg/L(P0.01)].The serum hs-CRP level was significantly correlated with degrees of carotid atherosclerosis(r=0.48,P0.01) and severity of stenosis in the extracranial carotid(r=0.51,P0.05). Conclusion: The serum hs-CRP level in patients with SCI is associated with carotid atherosderosis.
出处 《河南医学研究》 CAS 2011年第4期404-405,409,共3页 Henan Medical Research
基金 河南省医学科技攻关计划项目(201003118)
关键词 脑梗死 C反应蛋白 颈动脉粥样硬化 cerebral infarction C-reative protein carotid atherosclerosis
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