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血管内超声对糖耐量异常患者冠脉粥样斑块特点分析 被引量:4

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摘要 目的:对冠状动脉造影(CAG)显示轻中度狭窄病变进行血管内超声(IVUS)检查,分析糖耐量异常患者的冠脉粥样斑块病变特征及探讨其临床意义,探讨HbA1c水平与冠脉病变程度关系。方法:患者91例,糖耐量异常组(IGT组)50例,血糖正常组(NBG组)41例,均检测HbA1c。IVUS对两组患者病变血管进行定性和定量分析,测量靶病变的外弹力膜横截面积(EEMA)、最小管腔面积(MLA)、斑块面积(PA)、斑块负荷(PB)以及参考节段外弹力膜横截面积(REEMA)、管腔横截面积(RMAL)、参考节段斑块面积(RPA)、斑块负荷(RPB)。结果:IGT组HbA1c明显高于NBG组(P<0.05),IGT组冠状动脉内软斑块、偏心斑块和正性重构多见而钙化少,NBG组斑块多表现为硬斑块、钙化、无重构和负性重构(P<0.05);IGT组MLA<NBG组,而EEMA、PA和PB明显>NBG组(P<0.05),RMAL明显<NBG组,RPA、RPB则>NBG组(P<0.05),HbA1c水平与PA、PB呈正相关、与MLA呈负相关。结论:IVUS对评价冠脉轻中度病变有较高价值,IGT患者的冠脉病变程度较NBG患者严重和弥漫,HbA1c水平对判断冠状动脉病变程度可能有一定的价值。
出处 《实用医学杂志》 CAS 北大核心 2012年第2期234-236,共3页 The Journal of Practical Medicine
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参考文献8

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共引文献16

同被引文献48

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