摘要
目的总结8例支气管肺发育不良(BPD)患儿的6年临床随访结果。方法对温州医学院附属育英儿童医院2004年1月至2005年12月出生的8例BPD患儿分别在1、3和6岁龄时联系来院门诊随访或以电话随访,以探讨BPD的中远期随访结局。结果 1岁龄3例电话随访,5例来院随访;3岁龄2例电话随访,6例来院随访;6岁龄均来院随访。因肺炎或急性支气管炎反复再入院治疗:1岁以内8例22例次,～3岁3例6例次,～6岁1例次。1岁以内4例10例次出现喘息,～3岁3例6例次出现喘息,～6岁2例3例次出现喘息。6岁龄时常规肺通气功能检查5/8例(62.5%)提示小气道功能改变、轻度阻塞性通气功能障碍等;X线胸片检查显示两肺纹理增多增粗、紊乱,不规则实变影3例;毛玻璃样改变和囊泡形成3例;局限性肺气肿2例。结论 BPD患儿1岁龄时明显增加了再次入院风险,学龄前期趋于减少,但6岁时仍有62.5%病例提示常规肺通气功能异常,部分病例胸部影像学为毛玻璃样改变、囊泡形成和局限性肺气肿。
Objective To summarize the results of 8 cases with bronchopulmonary dysplasia （ BPD ） for 6 years clinical follow-up study. Methods Eight cases with BPD born at the Affiliated Yuying Children＇s Hospital of Wenzhou Medical College from January 2004 to December 2005 were contacted by out-patient follow-up or telephone at the age of 1, 3 and 6 years in order to explore the long-term outcome of BPD. Results Three cases of BPD children were contacted by telephone at 1 year old and 5 cases were contacted by out-patient follow-up at this age. Two cases of BPD children were contacted by telephone at 3 years old and 6 cases were contacted by out-patient follow-up at this age. Eight cases of BPD children were all contacted by out-patient follow-up at 6 years old. The re-hospitalization times were 22, 6 and 1 due to recurrent pneumonia or acute bronchitis at the age of 1, 3 and 6 years, respectively. The wheezing times were 10 （4 cases）, 6 （3 cases） and 3 （2 cases） at the age of 1, 3 and 6 years, respectively. Pulmonary function tests showed abnormalities in 5 cases （62.5 % ）, including small airway changes, mild obstructive ventilatory dysfunction, etc. Chest radiography showed ground grass opacity, vesicle formation in 3 cases, thickness or turbulence of texture in bilateral lungs, irregular opacity in 3 cases and local emphysema in 2 cases. Conclusions BPD significantly increased the risk of re-hospitalization after birth. It occurred commonly at the age of 1 year and decreased at pre-school age. Clinical follow-up at the age of 6 years found that 62.5% of the cases showed abnormal pulmonary function, and the characteristics of ground grass opacity, vesicle formation and local emphysema in chest image.
出处
《中国循证儿科杂志》
CSCD
2012年第1期55-58,共4页
Chinese Journal of Evidence Based Pediatrics
关键词
支气管肺发育不良
再入院
长期随访
Bronchopulmonary dysplasia
Re-hospitalization
Long-term follow-up
