摘要
目的:探讨知柏地黄丸联合复方丹参片对复发性口腔溃疡(ROU)患者血液流变学的影响,分析其变化与疗效关系。方法:对88例ROU患者,在知柏地黄丸联合复方丹参片治疗前后,分别进行血液流变学检测,将其结果进行对比分析,同时观察治疗效果。结果:治疗后,患者的全血黏度(高切和低切)、血浆黏度、血小板聚集率、红细胞聚集指数、纤维蛋白原、血沉7项指标,均有明显和非常明显下降(P<0.05或P<0.01)。红细胞压积与治疗前相比变化不明显(P>0.05)。结论:知柏地黄丸联合复方丹参片有明显降低ROU患者血液流变学增高状态的作用,并通过降低血液流变学多项指标增高水平,改善微循环,达到治疗效果。
Objective: To study the hemorheological effect of recurrent oral ulcers patients(ROU) with Zhibai Dihuang pills and Danshen tablets and to analyze the relation between its change and its effect.Methods: Hemorheological tests of 88 ROU patients were respectively made before and after the treatment and the results were compared and analyzed to observe the treatment effect.Results: After the treatment,the patients' whole blood viscosity(high shear and low shear),plasma viscosity,platelet aggregation,erythrocyte aggregation index,fibrinogen,erythrocyte sedimentation rate were very significantly decreased(P<0.05 or P<0.01),but Hematocrit did not change significantly compared with the pre-treatment(P>0.05).Conclusion: The integration of Zhibai Dihuang pills and Danshen tablets can significantly lower the blood rheology of the ROU patients and increase the levels of many indicators of the blood rheology and improve their microcirculation to achieve the therapeutic effect.
出处
《云南中医中药杂志》
2012年第1期24-26,4,共3页
Yunnan Journal of Traditional Chinese Medicine and Materia Medica
