摘要
目的:观察骨疏康颗粒联合阿仑磷酸钠(福善美)治疗脾肾两虚兼血瘀型骨质疏松症的疗效。方法:将65例患者随机分为治疗组和对照组,治疗组35例予骨疏康颗粒联合阿仑磷酸钠(福善美)治疗,对照组30例予阿仑磷酸钠(福善美)治疗。治疗8周后检测2组患者腰椎(L2～L4)骨密度(BMD),采用视觉模拟评分法(VAS)对疼痛分级及检测肝肾功。结果:腰椎(L2～L4)骨密度(BMD)治疗后治疗组较对照组显著增加(P<0.05);VAS疼痛评分治疗组较对照组明显减低(P<0.05);肝肾功治疗组与对照组无明显变化。结论:骨疏康颗粒联合阿仑磷酸钠(福善美)治疗骨质疏松症能显著增加腰椎(L2～L4)骨密度(BMD),明显减轻疼痛,而且不影响肝肾功。
Objective: To observe the effect of Gushukang granules combined with alendronate sodium(Fosamax) on the treatment of osteoporosis patients with spleen and kidney deficiency and blood stasis.Methods: 65 patients were randomly divided into one treatment group and one control group.35 patients in the treatment group were treated with Gushukang granules combined alendronate sodium(Fosamax) while 30 patients in the control group were only treated with alendronate sodium.After 8-week treatment,the lumbar spine(L2-L4) and bone conditions(BMD) of the patients in the two groups were detected by visual analog scales(VAS) for pain rating as well as liver and kidney test.Results: The lumbar spine(L2-L4) and the bone conditions(BMD) of the treatment group became better than that of the control group after the treatment(P<0.05).VAS pain score of the treatment group was significantly lower than that of the control group(P<0.05).The liver and kidney function of the treatment group and the control group showed no significant change.Conclusion: Gushukang granules combined with alendronate sodium can significantly improve the lumbar spine(L2-L4) and the bone conditions(BMD) of the patients and reduced their pain and does not affect the liver and kidney function,with good efficacy and safety
出处
《云南中医中药杂志》
2012年第1期26-28,4,共3页
Yunnan Journal of Traditional Chinese Medicine and Materia Medica
