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甲状腺癌实时超声造影增强特征与肿瘤大小的关系 被引量:35

Relationship between characteristics of thyroid carcinomas in real-time contrast-enhanced ultrasound and tumor sizes
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摘要 目的探讨甲状腺癌实时CEUS增强特征与结节大小的关系。方法将68例经手术病理证实的甲状腺癌患者按肿瘤最大直径分为〈10 mm1、0~20 mm、〉20 mm 3组,分析各组肿瘤的绝对始增时间、相对始增时间、增强的均匀性、有无灌注缺损、增强顺序、增强强度及增强时病灶边界。结果甲状腺癌增强多晚于周围甲状腺实质,以不均匀、向心性增强为主,且增强时病灶边界多数不清或欠清,3组间差异均无统计学意义(P〉0.05)。直径〈10 mm及10~20 mm甲状腺癌以低增强为主;直径〉20 mm的甲状腺癌以高增强为主。随着肿瘤直径增大,其内出现灌注缺损的概率增加,在3组中分别为28.57%(6/21)、54.29%(19/35)和75.00%(9/12),差异有统计学意义(P〈0.05)。结论甲状腺癌CEUS增强特征与肿瘤大小有一定关系;实时CEUS可为临床提供更多有价值的信息。 Objective To observe the relationship between characteristics of thyroid carcinomas in real-time CEUS and tumor sizes.Methods CEUS characteristics of 68 patients with thyroid carcinomas confirmed by pathology were retrospectively analyzed.The patients were divided into 10 mm group,10—20 mm group and 20 mm group according to maximum diameter of lesions.Absolute enhancement beginning time,relative enhancement beginning time,homogeneity,perfusion defect,enhancement order,enhancement intensity and enhancement margin type of each lesion during CEUS were evaluated.Results Most lesions enhanced later than surrounding thyroid gland.The predominant enhancement pattern in all three groups was heterogeneous concentric enhancement,and the most lesions showed less clear or poorly-defined margins after enhancement.There was no significant difference among three groups(P0.05).Thyroid carcinomas displayed low enhancement in 10 mm group and 10—20 mm group,while showed high enhancement in 20 mm group.With the increasing of lesion's maximum diameter,the probability of perfusion defect increased,i.e.28.57%(6/21),54.29%(19/35) and 75.00%(9/12) in 10 mm group,10—20 mm group and 20 mm group,respectively.There were significant differences among three groups(P0.05).Conclusion CEUS characteristics of thyroid carcinoma are related to the size of tumor to some extent.CEUS can provide valuable information for clinical diagnosis of thyroid carcinoma.
出处 《中国医学影像技术》 CSCD 北大核心 2012年第1期82-85,共4页 Chinese Journal of Medical Imaging Technology
基金 上海市浦东新区卫生系统优秀青年医学人才培养计划(PWRq2010-09) 上海市浦东新区卫生系统优秀学科带头人培养计划(PWRd2007-03)
关键词 甲状腺肿瘤 超声检查 肿瘤大小 Thyroid neoplasms Ultrasonography Tumor size
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