摘要
根据目前对乌头属中药有效成分的结构与药理作用的关系的研究现状,综述了乌头属中药有效成分的结构与其止痛、抗炎、局部麻醉、强心的药理作用及毒性的关系,为基于增效减毒目的的结构修饰提供参考。
Based on the advanced research of effective components of Aconitum species,the relationship between the structure and anti-inflammatory,analgesis,local anesthesia and pharmacological activities was reviewed.This paper may supply basic data for modifying the structure of constituents in Aconitum species for the improvement of effect and decrease of toxicity.
出处
《世界科学技术-中医药现代化》
2011年第6期1022-1026,共5页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家中医药管理局中医药行业科研专项(200807014):基于代谢组学的有毒中药毒性机理及解毒方法研究
负责人:王喜军
关键词
乌头属
有效成分
药理作用
构效关系
Aconitum species
effective components
pharmacological activity
structure-activity relationship
