摘要
目的 调查福建省碘缺乏病高危地区新发地方性克汀病（简称地克病）、地方性甲状腺肿流行现况及防治措施落实情况,为制订有针对性的防治策略措施提供科学依据.方法 2010年,在碘盐监测覆盖率较低的秀屿区、翔安区、平潭县、东山县各抽取3个乡（镇）,进行10岁以下新发地克病病例搜索；在每个乡（镇）抽取2所小学,每所小学抽取40名8～ 10岁儿童进行甲状腺B超检查,同时采集尿样,用砷铈催化分光光度法测定尿碘；在小学所在村抽取20名18 ～40岁育龄妇女,采集食用盐样和尿样,用半定量法测定盐碘,砷铈催化分光光度法测定尿碘.结果 病例搜索未发现新发地克病及疑似地克病病例；8 ～ 10岁儿童总体甲状腺肿大率为3.6％ （37/1027）,但东山县为5.4％（ 13/240）,超过国家消除碘缺乏病标准（＜5％）；8～10岁儿童和18～40岁育龄妇女的尿碘中位数分别为175.3、152.7 μg/L；碘盐覆盖率为82.7％ （382/462）.结论 福建省碘缺乏病高危地区未发现新发地克病及疑似地克病病例,人群尿碘中位数处于适宜水平.
Objective To investigate the occurrence of new cretinism cases and the prevalence of endemic goiter in iodine deficiency disorders（IDD） high-risk areas of Fujian province,so as to put forward target prevention and control measures for these areas.Methods Twelve counties from Xiuyu,Xiangan,Pingtan,and Dongshan were chosen into the survey by simple random sampling,searching for new cretinism cases were carried out in children under 10 years old.Two schools were chosen in every county and the thyroid volume of forty children aged 8 - 10 were determined by B-ultrasonography methods and their urinary iodine（UI） was determined by As3--Ce4＋catalytic spectrophotometry in each school.Twenty women of child-bearing age aged 18 - 40 were chosen for collecting edible salt and urine samples,and the salt iodine content was determined using self-quantitative kit and their UI was also determined by As3--Ce4＋ catalytic spectrophotometry.Results In the 4 high-risk counties,no cretinism cases were found.The goiter rate of children aged 8 - 10 was 3.6%（37/1027）,and that in Dongshan county was 5.4%（13/240）,which was higher than the national standards for eliminating IDD（ 〈 5%）.The median urinary iodine（MUI） of children aged 8 - 10 was 175.3 μg/L,and the MUI of women aged 18 -40 was 152.7 μg/L.The coverage rate of iodized salt was 82.7%（382/462）.Conclusions New case or suspected new case of cretinism is not discovered in the high-risk areas of IDD of Fujian province,and median urinary iodine level of people is in the adequate range.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2012年第1期68-70,共3页
Chinese Jouranl of Endemiology
基金
中央补助地方公共卫生专项资金地方病防治项目（2009）
关键词
碘
缺乏症
甲状腺肿
地方性
Iodine
Deficiency diseases
Goiter, endemic
