摘要
[目的]观察阿德福韦酯胶囊联合肝复胶囊治疗慢性乙型肝炎(CHB)肝纤维化的疗效。[方法]将67例CHB并发早期肝硬化患者随机分为治疗组(37例)和对照组(30例),2组均给阿德福韦酯抗病毒治疗,治疗组在此基础上加用肝复胶囊,疗程均为12个月,观察患者临床表现、生化指标、HBV-DNA、肝纤维化指标变化。[结果]治疗组临床症状、肝功能、肝纤维化指标的改善均优于对照组(P<0.05)。[结论]阿德福韦酯胶囊联合肝复胶囊是治疗CHB肝纤维化安全有效的药物,且无明显不良反应。
[Objective]To study the effect of the treatment for liver fibrosis of chronic hepatitis B with Adefovir Dipivoxil Capsule and Ganfu Capsule.[Methods]Total 67 cases were divided into two groups,the treatment（n=37）and control group（n=30）.Except for Adefovir Dipivoxil Capsule,which was given to both of two groups,the treatment group was administrated with Ganfu Capsule.The therapy course was 48 weeks for both guoups,and then indexes of hepatofibrosis,clinical manifestation,the index of liver function and HBV-DNA were evaluated.[Results]Clinical symptoms,the index of liver function and hepatic fibrosis in treatment group were obviously improved with a significant difference than control group（P〈0.05）.[Conclusion]Ganfu Capsule combined with Adefovir Dipivoxil Capsule can significantly improve liver fibrosis of chronic hepatitis B and without any obviously side effects.
出处
《中国中西医结合消化杂志》
CAS
2011年第6期394-396,共3页
Chinese Journal of Integrated Traditional and Western Medicine on Digestion
关键词
慢性乙型肝炎
肝纤维化
阿德福韦酯胶囊
肝复胶囊
chronic hepatitis B
hepatic fibrosis
Adefovir Dipivoxil Capsule
Ganfu Capsule
