摘要
目的为了减少银屑病患者外用糖皮质激素制剂致各种不良反应,探讨其发生机制及治疗方法。方法分别讨论68例银屑病患者各类皮质激素使用后发生不良反应的情况,治疗时采用随机的方法将68例患者分为两组,治疗组停用糖皮质激素制剂,外用萌尔夫软膏,1次/d,连续使用6周;对照组采用逐渐减少使用糠酸莫米松频率,直至停用的方法,其余治疗相同。结果治疗组在疗程结束时总有效率为75.76%;对照组在疗程结束时总有效率为48.57%,两组差异有显著性(P<0.05)。结论严格掌握银屑病患者外用激素制剂的适应证,避免激素不良反应的发生。萌尔夫在治疗银屑病的同时,还能治疗外用激素所致的各种不良反应。
Objective To reduce a variety of adverse reactions caused by corticosteroid preparations external used on psoriasis patients,to discuss its mechanism and treatment.Methods Discuss all kinds of adverse reactions of corticosteroid external use on 68 cases of psoriasis patients and the occurrence of adverse reactions;In thetreatment 68 patients were randomly divided into 2 groups,the treatment group used tacalcitol ointment instead of glucocorticoid preparations,topical,once daily,continuous use for 6 weeks,Control group gradually reduce the frequency of use of mometasone furoate cream,until out of the way.The rest treatments were all the same. Results At the end of treatment,the total effective rate was 75.76% in the control group,while at the end of treatment it was 48.57% in the control group.The difference was significant（P0.05）. Conclusion Topical steroid preparations should be strict controlled for psoriasis indication to avoid the occurrence of hormonal side effects.Mometasone furoate cream can also treat a variety of adverse reactions while treating psoriasis.
出处
《黑龙江医学》
2011年第12期920-922,共3页
Heilongjiang Medical Journal
关键词
银屑病
激素
不良反应
萌尔夫
Psoriasis
Hormone
Adverse reactions
Tacalcitol ointment
