摘要
目的研究肝癌破裂出血的原因和急性期止血以及止血后Ⅱ期治疗措施。方法对国内、外相关文献进行综述分析。结果肝癌破裂出血的病因目前仍不完全清楚,我国肝癌破裂出血与乙肝病毒感染导致抗原抗体复合物沉积于肿瘤小动脉壁致其损伤继而破裂出血关系密切。治疗方法有保守治疗、手术治疗(肝叶切除、肝动脉结扎术、缝扎填塞)、肝动脉插管栓塞术、其他治疗(无水乙醇瘤内注射、射频消融、生物免疫疗法等)。结论肝动脉插管栓塞术在肝癌破裂出血急性期止血效果良好,可作为Ⅱ期综合治疗的基础。
Objective To study the mechanisms of spontaneous rupture of hepatocellular carcinoma and the treatments in the acute phase and the second phase after hemostasis. Methods Related domestic and foreign literatures were reviewed. Results The mechanism of spontaneous rupture of hepatocellular carcinoma was still not quite clear.In China,spontaneous rupture of hepatocellular carcinoma was closely related with hepatitis B virus infection.Immune complex deposition in vessel wall led to the injuries of small arteries and bleeding.Treatments included conservative therapy,surgical intervention（lobectomy of liver,hepatic artery ligation,packing,and suturing）,transarteial embolization,other medications（percutaneous ethanol injection,radiofrequency ablation,bio-immunotherapy）. Conclusion Transarterial embolization has been shown to be highly effective in achieving immediate hemostasis,and can be used as the basis of phase two comprehensive treatment. 更多
出处
《中国普外基础与临床杂志》
CAS
2011年第12期1338-1343,共6页
Chinese Journal of Bases and Clinics In General Surgery
关键词
肝细胞癌
破裂出血
治疗
Hepatocellular carcinoma
Spontaneous rupture
Treatment
