摘要
目的探讨血清PⅠP、PⅢP、D-二聚体及cTnI水平与慢性心力衰竭的相关性。方法选取2009年1月至2010年12月于本院进行治疗的90例慢性心力衰竭患者为观察组,同时选取同期的90例健康体检者为对照组,将两组人员的血清PⅠP、PⅢP、D-二聚体及cTnI水平、心室重构程度进行统计检测及比较。结果观察组的血清PⅠP、PⅢP、D-二聚体及cTnI水平均显著高于对照组,且随着NYHA分级的增加,水平呈现上升趋势,与LVESD、LVESV呈正相关,与LVEF呈负相关,P<0.05或P<0.01,差异有统计学意义。结论血清PⅠP、PⅢP、D-二聚体及cTnI水平与慢性心力衰竭有较大的相关性,也可以反映心室重构的程度,值得进一步研究探讨。
Objective To study the correction between the serum level of PⅠP,PⅢP,D-D,cTnI and chronic heart failure（CHF）.Methods 90 patients with CHF,accepting therapy in our hospital from January 2009 to December 2010,were enrolled as observation group,and 90 healthy people at the same time were selected as control group,then the serum levels of PⅠP,PⅢP,D-D,cTnI and degree of ventricular remodeling of the two groups were detected and compared.Results The serum levels of PⅠP,PⅢP,D-D and cTnI in observation group were all significantly higher than those in control group,with an increasing tendency with the severity of NYHA Grade,be positive correlated with LVESD and LVESV,and be negative correlated with LVEF（P0.05 or P0.01）.Conclusion There could be fine correlation between serum level of PⅠP,PⅢP,D-D,cTnI and CHF.All of the indicators could be correlated with the degree of ventricular remodeling.And it could be worthy for further studying.
出处
《国际检验医学杂志》
CAS
2012年第2期176-177,共2页
International Journal of Laboratory Medicine
关键词
肌钙蛋白I
心室重构
心力衰竭
相关性
troponin
ventricular remodeling
heart failure
correction
