摘要
目的探讨咪达唑仑和丙泊酚联合应用于ICU机械通气患者的镇静效果。方法 ICU内300例机械通气患者根据入院顺序随机分为3组:单纯使用咪达唑仑组;单纯使用丙泊酚组;联合使用咪达唑仑和丙泊酚组,每组各100例,观察3组患者的镇静有效率、镇静时间以及ICU内停留时间。结果联合使用咪达唑仑和丙泊酚组与单纯使用丙泊酚组的的镇静时间明显短于联合使用单纯使用咪达唑仑组(P<0.05),联合使用咪达唑仑和丙泊酚组费用也明显少于单纯使用丙泊酚组(P<0.05),而在ICU内的停留时间,3个试验组之间没有差异。结论咪达唑仑和丙泊酚联合应用于ICU机械通气患者的镇静可有效提高镇静有效率,降低镇静时间,值得推广应用。
Objective To investigate the sedation effects of midazolam and propofol used in patients with mechanical ventilation ICU.Methods Totally 300 ICU patients with mechanical ventilation accorded to order of admission were randomly divided into three groups：simple to use midazolam group,simple to use propofol,combination of midazolam and propofol group,each 100 cases,observed three groups of patients with sedation efficient,calm time,and the ICU stay.Results The combined use of midazolam and propofol and simple to use propofol sedation group was significantly shorter in combination with midazolam alone group（P0.05）,combined use of midazolam and propofol group was significantly less than the cost of using propofol alone group（P0.05）,while the residence time in the ICU,there was no difference between the three experimental groups.Conclusions Midazolam and propofol used in ICU patients with mechanical ventilation with sedation can effectively improve the calm efficiency and reduce sedation time,should be widely applied.
出处
《医药论坛杂志》
2011年第23期42-43,共2页
Journal of Medical Forum
