摘要
目的探讨头孢拉定所致不良反应的特点和原因,以期为临床合理用药提供参考。方法 回顾性检索中国知网CHKD期刊全文数据库中报道的头孢拉定不良反应的文献,对其进行汇总分析。结果共检索到头孢拉定致不良反应168例,其中静脉给药占93.4%,1次给药剂量>1 g占82.86%,给药频次多为每日1次,症状以泌尿系统和过敏反应为主。结论临床应用头孢拉定时应严格掌握用药指征、用药剂量和间隔,以减少不良反应,保障患者用药安全。
Objective To discuss the characteristics and causes of cefradine-induced adverse reactions, so as to provide reference for the clinic rational application. Methods A pooled analysis was performed on the literatures of cefradine-induced adverse reactions retrieved in CHKD retrospectively. Results A total of 168 cases of adverse drug reaction caused by Cefradine were included, of which most was administed once a day by interverous （93.4 % ） and 〉 1 g at a time （ 83.2% ）. Urinary tract and allergic reaction were the main symptoms caused by Cefradine. Conclusion Cefradine should be strictly used according to its to reduce ADR and ensure patients＇ safty.
出处
《今日药学》
CAS
2011年第10期633-635,共3页
Pharmacy Today
关键词
头孢拉定
不良反应
文献
分析
cefradine ： adverse drug reaction
literature
analysis
