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自身免疫性淋巴增生综合征研究进展

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摘要 自身免疫性淋巴增生综合征（Autoimmune lymphoprolifera-tive syndrome,ALPs）是一种罕见的常染色体显性遗传病。其发病与Fas、Fas配体（Fas ligand,FasL）、Caspase-10或Caspase-8等细胞凋亡信号的基因突变所导致的T淋巴细胞凋亡缺陷有关。因1967年由美国的Canale和Smith首次报道,故又称Ca-nale-Smith综合征。
作者 许瑞蕊 周璐 王邦茂
机构地区 天津医科大学总医院消化内科
出处 《中华全科医学》 2012年第2期280-282,共3页 Chinese Journal of General Practice
关键词 自身免疫性淋巴增生综合征 FAS基因 T淋巴细胞凋亡
分类号 R551.2 [医药卫生—血液循环系统疾病]
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参考文献20

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二级参考文献48

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中华全科医学
2012年 第2期

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