摘要
目的：探讨MR扩散张量成像（MR-diffulsiontensorimaging，MR-DTI）表观扩散系数（ADC）和各向异性分数（FA）对不同病程颈脊髓压迫症的诊断价值。方法：2010年1月-2011年6月经MRI常规检查诊断为颈脊髓压迫症的患者50例，其中急性颈脊髓压迫患者15例（A组），均为外伤患者，在伤后72h内接受MRI检查；慢性颈脊髓压迫23例（B组），均为脊髓型颈椎病患者，病程超过6个月；慢性合并急性颈脊髓压迫12例（C组）,均有超过6个月的脊髓型颈椎病病史。且本次MRI检查前72h内受到颈部外伤累及颈髓。15例健康志愿者为对照组（D组），MRI常规检查颈脊髓未见异常。4组均行MR-DTI检查，测量A、B、C组患者颈脊髓受压处及D组C5／6椎间盘平面脊髓的ADC和FA，并行组间比较。结果：A、B、C、D组的ADC分别为（0．712±0．241）×10^-3mm^2／s、（1．012±0．256）×10^-3mm^2／s、（0．812±0．125）×10^-3mm^2／s、（0．823±0．106）×10^-3mm^2／s，FA分另4为0．401±0．098、0．472±0．095、0．496±0．172、0．541±0．158。A组ADC和FA与D组比较均明显降低（P〈0．05）；B组FA与D组比较明显降低、ADC明显增高（P〈0．05）；C组ADC与D组比较无显著性差异（P〉0．05），FA值低于D组（P〈0．05）。A组ADC及FA均低于B、C组（P〈0．05）；B组ADC高于C组，FA低于C组，组间差异有显著性（P〈0．05）。结论：MR-DTI的ADC及FA对不同病程颈脊髓压迫症有诊断价值。
Objectives： To study the diagnosis value of apparent diffusion coefficient （ADC） and fractional anisotropy （FA） of MR-diffusion tensor imaging （MR-DTI） for different courses of cervical cord compression. Methods： 50 patients with cervical cord compression were involved in this study from January 2010 to June 2011. These patients were divided into 3 groups, group A： acute cervical cord compression,gronp（n=15） underwent the cervical cord MRI within 72h after the injury; group B： chronic cervical cord compression group （n=23） had more than 6 months cervical myelopathy history; group C： chronic history with acute cervical cord compression group（n=12） had more than 6 months cervical myelopathy history and suffered from an acute cervical cord injury, and underwent the MR scan within 72h after the injury; group D included 15 healthy vol- unteers with normal MRI. All cases in 4 groups underwent MR-DTI.The values of ADC and FA in the com- pressed cervical cord in group A, B and C, and those at C5/6 in group D were meassured and compared. Results： The values of ADC in group A, B, C and D were （0.712±0.241）×10^-3mm^2/s、（1.012±0.256）×10^-3mm^2/s、（0.812±0.125）×10^-3mm^2/s and （0.823±0.106）×10^-3mm^2/srespectively, and the values of FA in group A, B, C and D were 0.401±0.098, 0.472±0.095, 0.496±0.172 and 0.541±0.158 respectively. Group A had significantly lower values of ADC and FA than group D（P〈0.05）; the FA decreased and ADC increased in group B com- pared with group D（P〈0.05）. The value of ADC had no change（P〉0.05）, but the value of FA decreased（P〈0.05） in group C compared with group D. Group A had lower values of ADC and FA than group B and C （P〈0.05）, and group B had higher value of ADC and lower value of FA than group C, which showed signif- icant difference（P〈0.05）. Conclusions： The ADC and FA under MR-DTI can determine different courses of cervical cord compression.
出处
《中国脊柱脊髓杂志》
CSCD
北大核心
2012年第2期147-151,共5页
Chinese Journal of Spine and Spinal Cord
关键词
颈脊髓压迫症
MRI
MR扩散张量成像
表观扩散系数
各向异性分数
Cervical cord compression
MRI
MR-diffusion tensor imaging
Apparent diffusion coefficient
Fractional anisotropy
