摘要
目的:探讨结直肠癌患者脂代谢异常的分布特征及其临床价值.方法:对于已经确诊的结直肠癌患者,测定患者术前血总胆固醇(total cholesterol,TC)、甘油三脂(triglyceride,TG)、高密度脂蛋白-胆固醇(high-density lipoprotein cholesterol,HDL-C)和低密度脂蛋白-胆固醇(low-density lipoprotein cholesterol,LDL-C),对所得数据进行统计学分析.结果:TC升高24例,正常135例;TG升高21例,正常138例;HDL-C升高13例,正常65例,降低81例;LDL-C升高22例,正常137例.患者血脂在不同年龄、肿瘤类型之间无显著差异,而在不同性别、肿瘤部位、肿瘤分期的患者血脂差异显著.结论:结直肠癌发生发展同脂代谢异常存在密切联系,性别、肿瘤部位、肿瘤分期对患者脂代谢异常有影响;而年龄、肿瘤类型对患者脂代谢影响不大,密切监测血脂变化有助于结直肠癌的防治.
AIM： To investigate the distribution characteristics and clinical signif icance of lipid metabolism abnormalities in patients with colorectal cancer. METHODS： Total cholesterol （TC）, triglyceride （TG）, high-density lipoprotein cholesterol （HDL-C） and low-density lipoprotein cholesterol （LDL-C） were measured in patients with colorectal cancer, and all the data were analyzed. RESULTS： Of all the patients, 24 had elevated levels of TC, and 135 had normal TC levels; 21 had elevated levels of TG, and 138 had normal TG levels; 13 had elevated levels of HDL-C, 65 had normal HDL-C levels, and 81 had reduced HDL-C levels; 22 had elevated levels of LDL-C, and 137 normal LDL-C levels. These lipid parameters had no obvious correlation with ageor tumor type, but were signif icantly correlated with gender, tumor location and tumor stage. CONCLUSION： Patients with colorectal cancer often develop lipid metabolism abnormalities. Gender, tumor location and stage were closely associated with lipid metabolism in patients with colorectal cancer, while age and tumor type had no signif icant in？ uence on lipid metabolism in these patients.
出处
《世界华人消化杂志》
CAS
北大核心
2011年第34期3542-3545,共4页
World Chinese Journal of Digestology
关键词
脂代谢异常
结直肠癌
临床特征
Colorectal cancer
Lipid metabolism
Clinical signifi cance
