摘要
目的调查我院体检人群中痛风及无症状高尿酸血症的基本情况,分析饮食、饮酒、肥胖等因素对其的影响,从而筛选无症状高尿酸血症人群发生痛风的危险因素。方法对2010年5-8月在我院体检的1 209例人员进行调查,其中34例确诊的痛风患者为痛风组,63例无症状高尿酸血症者为高尿酸组,血尿酸正常人群中抽取118例为对照组,探讨饮食、饮酒、肥胖等方面的危险性。结果蔬菜、奶类、酒精摄入量和腰围在痛风组、高尿酸组和对照组间比较差异有统计学意义(P<0.05);痛风组和高尿酸组在酒精摄入量、腰围比较差异有统计学意义(P<0.05)。对酒精摄入量、腰围进行回归分析腰围OR为0.090,P为0.022<0.05;酒精摄入量OR为0.646,P为0.019<0.05。结论中心性肥胖、酒精摄入量是高尿酸血症人群发生痛风的危险因素。
Objective To analyze the effect of diet, drinking and obesity on gout in patients with asymptomatic hyperuricemia by investigating their general condition. Methods Among the 1 209 persons who underwent physical and health examination in our hospital in May-August 2010, 34 who were diagnosed as gout served as a gout group, 63 with asymptomatic hyperuricemia served as a hyperuricemia group, and 118 with normal uric acid served as a control group. Effect of diet, drinking and obesity on gout was studied. Results The intake of vegetables, dairy and alcohol, and the waistline were significantly different among the 3 groups（P〈0.05）. The alcohol intake and waistline were significantly different between the gout and hyperuricemia groups（P〈0.05）. Logistic regression analysis showed that the OR was 0.090 for waistline and 0.646 for alcohol intake（P〈0.05）. Conclusion Central obesity and alcohol intake are the risk factors for gout in patients with asymptomatic hyperuricemia.
出处
《军医进修学院学报》
CAS
2012年第2期135-136,147,共3页
Academic Journal of Pla Postgraduate Medical School
基金
黑龙江省卫生厅医学科研课题(2009092)
哈尔滨医科大学附属第一医院2008年院基金资助项目(Q08-029)
关键词
嘌呤类
饮酒
肥胖
痛风
高尿酸血症
purines
alcohol drinking
obesity
gout
hyperuricimia
