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特异性免疫治疗安全性及不良反应处理措施 被引量:2

The safety of allergy specific immunotherapy and treatment of its side effects
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摘要 特异性免疫治疗主要包括皮下免疫治疗(SCIT)和舌下免疫治疗(SLIT),经全世界各国医生临床研究表明是安全的。它的不良反应主要是过敏反应,常见为局部表现,但严重全身性不良反应可以威胁患者生命甚至死亡。不良反应常见于剂量递增阶段,SCIT注射后短时间内出现手心和脚底烧灼感、痒感和热感,全身荨麻疹是严重全身不良反应的前驱症状,应立即肌注或静注抗阻胺药,出现低血压症状立即肌注肾上腺素;在治疗前与患者做好沟通,遵守其说明书的要求,注意其危险因素,同时在治疗早期联合药物治疗控制患者过敏性疾病的症状,可以有效减少免疫治疗的不良反应。 Summary :Allergy specific immunotherapy included subcutaneous immunotherapy and sublingual immunotherapy( SLIT), it was safety. According to clinic researches of doctors all over the world. The side effects of it was allergy, which often appear during the up-dosing regimen, as local was more common, but anaphylactic reaction might cause death. If the patient felt burn and itch of the palm and foot or systemic Urticaria in a short time after injection,it was the premonitory symptom of anaphylaxis, Muscle or intravenous injection of Antihistamine should be done immediately. If hypotension was occurred, Muscle injection of adrenaline. The adverse reaction should be avoided, if medical staffs have good communication with patient before the treatment, follow the instructions,Pay attention to the risk factors and combine with pharmacotherapy to control symptoms of allergic disease.
作者 赖荷
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2012年第2期102-104,共3页 Chinese Journal of Practical Internal Medicine
关键词 特异性免疫治疗 皮下免疫治疗 舌下免疫治疗 allergy specific immunotherapy subcutaneous immunotherapy sublingual immunotherapy
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