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多药耐药菌的目标性监测与干预效果分析 被引量:6

Targeted surveillance of multidrug-resistant bacteria and effect of intervention
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摘要 目的了解多药耐药菌目标性监测的数据,评价监测与干预的效果。方法前瞻性监测与时时干预,利用χ2检验比较2009年及2010年耐甲氧西林金黄色葡萄球菌(MRSA)的分离率、医院获得性MRSA(HA-MRSA)的构成比及在ICU分布。结果 2009年共收集金黄色葡萄球菌165株,检出MRSA75株,检出率为45.5%,其中HA-MRSA为53株,占70.7%;2010年共收集金黄色葡萄球菌228株,检出MRSA 61株,检出率为26.8%,其中HA-MRSA为33株,占54.1%;两年的MRSA检出率及HA-MRSA所占比率比较,差异有统计学意义(χ2=14.792,P<0.01;χ2=3.972,P<0.05)。结论监测和干预措施效果明显。 OBJECTIVE To analyze the data on multidrug-resistant organism supervision and to evaluate the effect of supervision and intervention. METHODS Prospective supervision and on-site intervention were performed to collected specimen,and χ2 statistical method was used to compare the separation rate,the constituent ratio,and the distribution. RESULTS Totally 165 strains of Staphylococcus aureus were collected in 2009,and 75 strains of MRSA were detected with the detection rate of 45.5%,among which,53 strains were HA-MRSA,accounting for 70.7%;totally 228 strains of S.aureus were collected in 2010,61 strains of MRSA were detected with the detection rate of 26.8%,among which 33 strains were HA-MRSA,accounting for 54.1%.The differences of detection rate of MRSA and the percentage of HA-MRSA between 2009 and 2010 were statistically significant(χ2=14.792,P0.01;χ2=3.972,P0.05). CONCLUSION Surveillance and intervention measures have significant effect in preventing and controlling infection.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2012年第3期586-587,共2页 Chinese Journal of Nosocomiology
基金 苏州市科技发展计划指导项目(SZD09104)
关键词 多药耐药菌 监测 干预 Multidrug-resistant organism Supervision Intervention
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  • 1舒雪芹,方晔,石娜,周铁丽,廖洪菊.医院环境中葡萄球菌监测[J].中华医院感染学杂志,2004,14(7):771-772. 被引量:11
  • 2卫生部办公厅.医院感染监测规范[M].北京:人民卫生出版社,2009:12.
  • 3卫生部办公厅.多重耐药菌医院感染预防与控制技术指南(试行)[M].北京:人民卫生出版社,2011:1.17.
  • 4樊丹,柴玉.卫生部要求加强多药耐药菌医院感染控制工作[N].中国中医药报,2008.
  • 5胡必杰,郭燕红,高光明,等.医院感染预防与控制标准操作规程[M].第2版.上海:上海科学技术出版社,2010:165-166.
  • 6Miao J,Du YZ,Yuan H,et al.Drug resistance reversal activity of anticancer drug loaded solid lipid nanoparticles in multidrug resistant cancer cells[J].Colloids Surf B Biointerfaces,2013(110):74-80.
  • 7Milane L,Duan Z,Amiji M.Role of hypoxia and glycolysis in the development of multi-drug resistance in human tumor cells and the establishment of an orthotopic multi-drug resistant tumor model in nude mice using hypoxic pre-conditioning[J].Cancer Cell Int,2011(11):3.
  • 8Vivek R,Thangam R,NipunBabu V,et al.Multifunctional HER2-antibody conjugated polymeric nanocarrier-based drug delivery system for multi-drug-resistant breast cancer therapy[J].ACS Appl Mater Interfaces,2014,6(9):6469-6480.
  • 9Klevens RM, Morrison MA, Nadle J, et al. Invasive methicillin- resistant Staphylococcus aureus infections in the United States [J].JAMA, 2007, 298 (15): 1763-1771.
  • 10Paul H. Me Cay, Alain A. Ocampo-Sosa and Gerard T. A. Fleming, Effect of subinhibitory concentrations of benzalkonium chloride on thecompetitiveness of Pseudomonas aeruginosa grown in continuousculture [J].Microbiology, 156 (2010) ,30-38;DOI 10. 1099/mic. 0. 029751-0.

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