期刊文献+

肝门部胆管癌手术方式的正确选择 被引量:30

Appropriate choice of surgical strategies in managing hilar cholangiocarcinoma
原文传递
导出
摘要 肝门部胆管癌由Klatskin在1965年首次描述,是指发生在左肝管、右肝管、左右肝管分叉部和肝总管上段的胆管黏膜上皮恶性肿瘤。其发病率近30年来有增加趋势,占胆道肿瘤的67%,多数患者预后差,术后5年的生存率〈30%,根治性R0切除是目前惟一可能获得治愈或提高长期生存率的方法。由于肝门部胆管癌解剖的复杂性以及肿瘤本身具有肝转移、淋巴结转移、周围血管侵犯及神经浸润的生物学特性,其手术治疗仍然颇为棘手。 Hilar cholangiocareinoma is a rare tumor with a poor prognosis. Due to advances in preoperative imaging and enhanced comprehension of tumor biological behavior, surgical management of hilar cholangiocarcinoma has evolved since its original description. Currently, it has been accepted that complete surgical resection provides the only possibility for cure or long-term survival, however, the surgical management of hilar cholangiocarcinoma is extremely challenging because of its anatomical location and vascular proximity. In order to achieve complete resection, several surgical approaches have been investigated and evaluated regarding major hepatic resection, lymph node dissection, vascular resection, extended resection and liver transplantation, however, there are still many disputa- tions. Furthermore, many surgical technical difficulties exist in biliary reconstruction after resection owing to anatomical problems. Focusing on the disputes and problems mentioned above, we herein review and discuss surgical strategies in managing hilar cholangiocarcinoma.
作者 彭承宏 程坤
出处 《中华消化外科杂志》 CAS CSCD 北大核心 2012年第1期11-14,共4页 Chinese Journal of Digestive Surgery
基金 基金项目:上海市科委基础重点项目(09JC1410100)
关键词 胆管肿瘤 肝门部 肝切除术 外科手术 Cholangiocarcinoma, hilar Hepatectomy Surgical procedures, operative
  • 相关文献

参考文献29

  • 1Klatskin G.Adenocarcinoma of the hepatic duct at its bifurcation within the porta hepatis.An unusual tumor with distinctive clinical and pathological features.Am J Med,1965,38:241-256.
  • 2Deoliveira ML,Schulick RD,Nimura Y,et al.New staging system and a registry for perihilar cholangiocarcinoma.Hepatology,2011,53(4):1363-1371.
  • 3Unno M,Katayose Y,Rikiyama T,et al.Major hepatectomy for perihilar cholangiocarcinoma.J Hepatobiliary Pancreat Sci,2010,17(4):463-469.
  • 4Ercolani G,Zanello M,Grazi GL,et al.Changes in the surgical approach to hilar cholangiocarcinoma during an 18-year period in a Western single center.J Hepatobiliary Pancreat Sci,2010,17 (3):329-337.
  • 5Igami T,Nishio H,Ebata T,et al.Surgical treatment of hilar cholangiocarcinoma in the "new era":the Nagoya University experience.J Hepatobiliary Pancreat Sci,2010,17 (4):449-454.
  • 6Young AL,Prasad KR,Toogood GJ,et al.Surgical treatment of hilar cholangiocarcinoma in a new era:comparison among leading Eastern and Western centers,Leeds. J Hepatobiliary Pancreat Sci,2010,17(4):497-504.
  • 7Lee SG,Song GW,Hwang S,et al.Surgical treatment of hilar cholangiocarcinoma in the new era:the Asan experience.J Hepatobiliary Pancreat Sci,2010,17 (4):476-489.
  • 8Hidalgo E,Asthana S,Nishio H,et al.Surgery for hilar cholangiocarcinoam:the Leeds experience.Eur J Surg Oncol,2008,34(7):787-794.
  • 9van Gulik TM,Kloek JJ,Ruys AT,et al.Multidisciplinary management of hilar cholangiocarcinoma (Klatskin tumor):extended resection is associated with improved survival.Eur J Surg Oncol,2011,37(1):65-71.
  • 10Ikeyama T,Nagino M,Oda K,et al.Surgical approach to bismuth Type Ⅰ and Ⅱ hitar cholangiocarcinomas:audit of 54 consecutive cases.Ann Surg,2007,246(6):1052-1057.

二级参考文献38

共引文献39

同被引文献274

引证文献30

二级引证文献175

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部