1Hauke W, K6hler G, Henneicke-von Zepelin H H, et al. Es- beritox~ N as supportive therapy when providing standard anti- biotic treatment in subjects with a severe bacteria] infection ( a- cute exacerbation of chronic bronchitis) : A multicentrie, pro- spective, double-blind, placebo-controlled study [ J ]. Chemo- therapy, 2002, 48(4-5): 259-266.