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参附注射液对脓毒症患者TNF-α、IL-6、IL-8水平的影响 被引量:30

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摘要 目的观察脓毒症患者肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)、白介素-8(IL-8)的变化,探讨参附注射液对多器官功能障碍(MODS)的影响。方法脓毒症患者56例随机分为实验组和对照组各28例。对照组采用常规治疗,实验组在此基础上,给予参附注射液静脉滴注。在入院后第2天(治疗前)及入院后12d(治疗后)抽取静脉血检测TNF-α、IL-6、IL-8。结果实验组治疗后TNF-α、IL-6、IL-8含量的降低程度大于对照组。结论参附注射液可以抑制炎性因子TNF-α、IL-6、IL-8过量表达,防止MODS的发生与发展。
作者 庄育刚
出处 《中国中医急症》 2012年第2期299-300,共2页 Journal of Emergency in Traditional Chinese Medicine
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参考文献8

  • 1Angus DC, Linde-Zwirble WT, Lidicker J, et al. Epidemiology of se- vere sepsis in the United States : analysis of incidence, outcome,and associated costs of care[J]. Crit Care Med,2001,29(10) : 1303-1310.
  • 2俞森洋.严重脓毒症和脓毒性休克的治疗新进展[J].临床肺科杂志,2009,14(4):427-429. 被引量:13
  • 3Luzzani A,Polati E,Dorizzi R,et al. Comparison of procalcitoninand C-reactive protein as markers of sepsis[J]. Crit Care Med,2003,31 (6) : 1737-1741.
  • 4杜斌,李毅,陈德昌,潘家绮.血清降钙素原和白细胞介素6检测在感染和非感染性全身性炎症反应鉴别诊断中的作用[J].中华医学杂志,2002,82(16):1111-1114. 被引量:55
  • 5Kocabas E, Sarikcioglu A. C-react iveprotein, interleukin-6, i nter- leukin-8 and tumor necrosis factoral phainthe diagnosis of nenatal sepsis[J]. Turk J Ped iatr,2007,49 ( 1 ) :7-20.
  • 6么国旺,殷宗福.MODS发病机制中IL-1、IL-6/IL-10阴阳相关属性[J].中国中西医结合外科杂志,2007,13(6):577-580. 被引量:2
  • 7Caini S ,Koldkjaer OG, Pederson C, et al. Procalcitonin ,hpopo-lysac- charide-binding protein,interleukin-6and C-reactive proteinin com- munity-acquired infections and sepsis: a prospective study[J ]. Crit Care, 2006,10(2) : R53.
  • 8Vindenes H, Ulves t acl E, Bierknes R. Ncreased levels of circul at ing interleukin 8 in patient s with large burn : relat ion t o burn size and sepsis[J]. J Trauma. 1995, 39(5) : 635- 640.

二级参考文献16

  • 1王红伟.论免疫学中的阴阳观[J].中医教育,2004,23(5):48-49. 被引量:2
  • 2崔乃强,赵琪,葛智慧,殷宗福,靳殿功,孙新明,邱奇,张灼,张风云,房洁,吴咸中.通里攻下法治疗急腹症所致MODS的疗效观察[J].中国中西医结合外科杂志,1996,2(5):315-320. 被引量:74
  • 3Lakshmi Durairaj, MD; and Gregory A. Schmidt, Fluid Therapy in Resuscitated Sepsis. Less Is More. Chest, 2008,133:252 - 263.
  • 4Wheeler AP. Recent Developments in the Diagnosis and Management of Severe Sepsis. Chest, 2007,132 : 1967 - 1976.
  • 5Dellinger RP, levy MM, Carlet JM, et al. Surviving sepsis campaign:intemational guidelines for management of severe sepsis and septic shock:2008. Crit Care Med,2008,36( 1 ) :296 -327.
  • 6Dellinger R P, Cadet J M, Masur H, et al. Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock[J]. Intensive Care Meal,2005, 30 (4): 536.
  • 7Pinsky MR. Dysregulation of the immune response in severe sepsis[J]. Am Med Sci, 2.006, 328: 220.
  • 8Kluth DC, Rees AJ. Inhibiting inflammatory cytokines [ J ]. Semin Nephrol, 1996, 1(6): 576.
  • 9L. Lind,E. Bucht,S. Ljunghall. Pronounced elevation in circulating calcitonin in critical care patients is related to the severity of illness and survival[J] 1995,Intensive Care Medicine(1):63~66
  • 10李利清.中西医结合免疫与共鸣学说初探[J].国医论坛,1999,14(2):13-14. 被引量:1

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