摘要
目的:研究归芪多糖颗粒制剂的成型工艺。方法:以吸湿性、溶解度、成型率为指标,筛选出处方中加入辅料的品种、配比及最佳成型工艺。结果:最佳制粒工艺条件为原料-甘露醇-聚维酮(PVP)1∶0.9∶0.1,润湿剂为玉米朊乙醇液。结论:颗粒制剂所选辅料合理,成型制备工艺简便可行。
Objective：To study on forming technology of Guiqi polysaccharide granule.Method：With hygroscopicity,solubility and forming rate as index,kinds and ratio of excipients and optimum forming process of formulation were screened out.Result：Optimum granulating condition：ratio of raw materials-mannitol-PVP was 1∶0.9∶0.1,wetting agent was zein ethanol solution.Conclusion：Selected excipients of granule was reasonable,molding technology was convenient and feasible.
出处
《中国实验方剂学杂志》
CAS
北大核心
2012年第4期32-34,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
国家自然科学基金项目(2007BA137B00)
关键词
归芪多糖
颗粒剂
成型工艺
Guiqi polysaccharide
granule
formulation process
