摘要
目的分析体检人员的生化指标与骨密度的相关性。方法收集2008年1月至2010年11月在本院体检中心行骨密度检测的3025名体检者血糖、血脂、血尿酸、血压等指标。测定患者腰椎1—4（L1-4）和全髋的骨密度值。统计分析，使用SPSS13．0软件。在分析骨密度与其他因素的相关关系，先进行线性相关分析，将与骨密度存在线性相关的因素再行多重线性回归分析。结果经多重线性回归分析，发现与男性全髋骨密度存在相关性的因素有：年龄，体重，碱性磷酸酶；与男性腰椎（L2-4）骨密度存在相关性的因素有：体重，碱性磷酸酶，谷氨酰转肽酶；与女性全髋骨密度存在相关性的因素有：年龄，体重，碱性磷酸酶，谷氨酰转肽酶；与女性腰椎（L2-4）骨密度存在相关性的因素有：年龄，体重，碱性磷酸酶，中性粒细胞比值。结论本研究的体检数据显示，体重和骨密度呈正相关，碱性磷酸酶和骨密度呈负相关，血糖、血脂等生化指标与骨密度的关系还需要进一步探讨。
Objective To analyze the correlations between bone mineral density and biochemistry data of health checkup receivers. Methods A total of 3025 sets of medical measurements, including blood glucose, lipid profiles, blood uric acid, blood pressure and bone mineral density, were collected from January 2008 to November 2010 in Medical Examination Center of Peking Union Medical College Hospital. Bone mineral density of lumbar vertebra 1 - 4 （L1-4） and hip were recorded. Linear correlation analysis was used to investigate the correlation between bone mineral density and other factors. Results In multiple regression analysis, age, body weight, and alkaline phosphatase level were found to be related to male hip bone mineral density; age, body weight, alkaline phosphatase, and glutamyltranspetidase level were related to male L2-4 bone mineral density; age, body weight, alkaline phosphatase, and glutamyhranspetidase level were indicated to be related to female hip bone mineral density; age, body weight, alkaline phosphatase, and the ratio of neutrophile granulocyte were related to female L2-4 bone mineral density. Conclusion In this study group, body weight was positively correlated with bone mineral density, although alkalinephosphatase was negatively associated with bone mineral density. The role of blood glucose and lipid in the regulation of bone mineral density remains inconclusive.
出处
《中华健康管理学杂志》
CAS
2012年第1期28-31,共4页
Chinese Journal of Health Management
关键词
骨密度
体格检查
生化数据
Bone density
Physical examination
Biochemistry data
