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从三维放射治疗技术进展思考Ⅳ期非小细胞肺癌的胸部放疗 被引量：5

From Three - dimensional Radiation Therapy Technology Progress Thinking Chest Radiotherapy Effect for Stage IV Non - small Cell Lung Cancer
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摘要 思考和探索三维放射治疗Ⅳ期非小细胞肺癌（Non-small Cell Lung Cancer,NSCLC）原发肿瘤（包括引流区转移淋巴结）,提高生存期的可行性和重要性.分析Ⅳ期NSCLC的研究文献,回顾化学药物治疗的现状、不足和必要性,分析远处转移特点给予局部放疗的可能,评价二维放射治疗前瞻性研究结果获得的优势和缺陷,思考三维放射治疗的基础对开展胸部放疗研究的必要性,探索并实践化疗同期胸部三维放射治疗Ⅳ期NSCLC延长生存期的可能性.Ⅳ期NSCLC通过细胞毒药物治疗获得延长生存期和改善生活质量,但有限;胸部二维放疗肯定改善患者生活质量,延长生存期作用有争议,但研究设计有缺陷;胸部三维放疗显著降低损伤、提高近期疗效.实践证明,化疗同期胸部三维放射治疗Ⅳ期NSCLC前瞻性研究从总体生存和毒性反应、局部有效率、局部剂量、不同转移器官等四个方面分析,对生存均具有显著的影响.化疗同期胸部三维放射治疗IV期NSCLC可以使部分病例从放疗中获得显著延长生存期的益处.
作者 卢冰
机构地区 贵州省肿瘤医院／贵阳医学院附属肿瘤医院胸部肿瘤科
出处 《实用肿瘤学杂志》 CAS 2012年第1期55-59,共5页 Practical Oncology Journal
基金 贵州省科技公关项目（黔科合SY[2010]3078号） 贵州省科学技术自然基金（黔科合J字[2010]2186号）
关键词 Ⅳ期非小细胞肺癌 胸部三维放射治疗 胸部病灶/原发灶/引流区转移淋巴结 同期放化疗 前瞻性研究
分类号 R734.2 [医药卫生—肿瘤]
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参考文献38

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二级参考文献44

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共引文献54

同被引文献29

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引证文献5

二级引证文献9

实用肿瘤学杂志
2012年 第1期

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