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脂肪肝MRI同反相位定量测量与CT值相关分析 被引量:10

Relationship between quantitative measurement of fatty liver with in-phase and out-of-phase of MRI and CT attenuation value
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摘要 目的:分析脂肪肝MRI同反相位定量测量与CT值相关性,并评价MRI同反相位定量测量判断脂肪肝的价值。方法:回顾性分析86例临床疑诊脂肪肝而行CT、MRI检查病例,测量相应的CT值及同反相位上的MR信号,计算3个CT值比及4个信号指数。使用Pearson相关分析3个CT值比与4个信号指数间的相关性,并以CT值肝/脾≤1作为脂肪肝标准,计算不同阈值下信号指数判断脂肪肝的敏感性、特异性和准确性。结果:各CT值比与各信号指数间均呈明显负相关(r=-0.823~-0.917),其中以CT值肝/脾与信号指数1之间的相关性最高(r=-0.917,P=0.000)。以CT值肝/脾≤1作为脂肪肝标准,判断脂肪肝时,信号指数1、信号指数4均以阈值≥0.1最佳,准确性分别为86.05%和89.53%。结论:CT值肝/脾与MRI同反相位定量测量有很好的相关性,两者都能作为脂肪肝定量评价的手段,并且能互为补充。以信号指数1或信号指数4≥0.1的标准诊断脂肪肝是合适的。 Objective: To analyze the relationship between quantitative measurement of fatty liver with in-phase and out-of-phase of MRI and CT attenuation value,and to evaluate the application of the quantitative measurement with in-phase and out-of-phase of MRI in the diagnosis of fatty liver.Methods: Signal intensity of in-phase and out-of-phase of MRI and CT attenuation value were measured retrospectively in 86 patients clinically suspected fatty liver.Three CT attenuation value ratios and 4 signal indexes were calculated and the relationship between the CT attenuation value ratios and the signal indexes were analyzed by Pearson correlation coefficient.The sensitivity,specificity,accuracy of signal indexes for diagnosing fatty liver at different thresholds were calculated.Results: Significantly negative correlations were shown between 3 CT attenuation value ratios and 4 signal indexes(r=-0.823~-0.917),with the highest correlation between CT attenuation value ratio of liver to spleen and signal index 1(r=-0.917,P=0.000).Signal index 1 and signal index 4 had relatively high accuracies for diagnosing fatty liver with the threshold ≥0.1 for both,with the accuracy of 86.05% and 89.53% respectively,using CT attenuation value ratio of liver to spleen ≤1 as the standard.Conclusion: Quantitative measurement with in-phase and out-of-phase of MRI significantly correlate to CT attenuation value ratio of liver to spleen,and both can be used for quantitative evaluation of fatty liver.Signal index 1 or signal index 4 is optimal in diagnosing fatty liver with the threshold ≥0.1.
出处 《中国临床医学影像杂志》 CAS 2012年第2期81-84,共4页 Journal of China Clinic Medical Imaging
关键词 脂肪肝 磁共振成像 体层摄影术 螺旋计算机 Fatty liver Magnetic resonance imaging Tomography spiral computed
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