摘要
口腔扁平苔藓(OLP)的癌变问题一直争论很大。作者从1985年来对收治的596例OLP患者进行了为期10年的追踪随访观察,平均随访时间为7年,这些OLP患者均在病理上有“符合扁平苔藓”的诊断,且均有2～3次活检,至少每年随访一次。在这10年中,发现OLP癌变的病例7例,从这7例OLP癌变的病例分析中发现,癌变与不适当的治疗和对外界致癌因素敏感有关。从发生部位看,无一例发生在口腔粘膜的3个危险区。从临床病损类型看,糜烂型的OLP应视为癌变的高危病损。
There are controversy on the cancer transformation of oral lichen planus(OLP). The auther of this article followed up 596 OLP patients for ten years, averged 7 years. At least examed once every year, all patients were biopsied 2～3 times,and diagnosed as “Lichen planus” in histopathology. Seven OLP Lesions developed into carcinoma. The research results sugested that the cancer transformation of OLP was associated with improper treatment and outside stimulation. In the seven patients of cancer transformation, none appeared in the three dangerous region of oral cavity. Also,the results suggest that the erosive form of OLP are dangerous for cancer transformation.
出处
《临床口腔医学杂志》
2000年第1期52-53,共2页
Journal of Clinical Stomatology
