摘要
目的:探讨喷雾型抗菌膜用于肛裂保守治疗的有效性及安全性。方法:采用前瞻性随机对照临床试验方法,将96例肛裂患者随机分为两组,治疗组50例,早、中、晚每次用0.1%的安尔碘消毒肛门创面后,再用喷雾型抗菌膜外喷肛门创面1～2喷;对照组46例,用1:5000高锰酸钾溶液500～1000ml温水坐浴,2次/日,每次15分钟。均连用1周。结果:治疗组痊愈34例(68.00%),好转13例(26.00%),有效率94.00%,对照组痊愈18例(39.13%),好转16例(34.78%),有效率73.91%,治疗组出血、疼痛、瘙痒、水肿、糜烂的减轻程度以及创面愈合明显优于对照组(P<0.05),两组均未出现全身不良反应。结论:喷雾型抗菌膜用于治疗肛裂的临床效果明显,安全性高,无明显不良反应。
Objective：To evaluate the efficiency and safety of Antibacterial membrane for the conservative treatment for anal fissure.Methods：With prospective randomized comparative clinical methods,96 cases were ramdomly divided into two groups.Among them,50 were given the Antibacterial membrane three times a day after disinfection,and the remaining 46 received potassium permanganate as contral group.Result：The treatment recover 34 example（68.00%）,improve 13 example（26.00%）,effective rate 94.00%,the contral group recover 18 example（39.13%）,improve 16 example（34.78%）,effective rate 73.91%.After the treatment,Antibacterial membrane group showed less bleeding、pain、itching and better recovery than the contral group（P0.05）.No systemic adverse reactions were found in both groups.Conclusion：Antibacterial membrane is a better method in treating anal fissure and has no obvious side effects.
关键词
喷雾型抗菌膜
肛裂
保守治疗
Antibacterial membrane
Anal fissure
Conservative treatment
