摘要
目的 本文对女性抑郁症患者的血清胆固醇水平与自杀行为的关系进行了探讨。方法 对 116例样本进行血清胆固醇水平测定 ,其中抑郁症伴自杀行为的 40例 ,抑郁症不伴自杀行为的 3 6例 ,正常人 40例。结果 抑郁症伴有自杀行为组血清胆固醇水平明显低于无自杀行为组和正常对照组。血清胆固醇水平与自杀的严重程度呈明显相关。结论 我们认为低血清胆固醇水平可增加女性抑郁症自杀的风险。推测低血清胆固醇导致的自杀行为可能与中枢 5 羟色胺 ( 5 HT)功能降低有关。
Objective To determine the relation between low cholosterol levels and depression with suicidal behavior in women.Methods The serum cholesterol level was examined in 116 women including 40 depressive patients with suicidal behavior, 36 depression patients without suicidal behavior and 40 healthy subjects.Results The serum cholesterol levels of patients with serious suicidal behavior were siginficantly lower than those of patients without suicidal behavior and healthy women.Conclusions These results suggest but do not confirm that the low serum cholesterol levels may increase the risk of suicide in female depressive patients. A relationship between low cholesterol level and lower activity of central serotonergic function is hypothesized.
出处
《中国神经精神疾病杂志》
CAS
CSCD
北大核心
2000年第2期78-80,共3页
Chinese Journal of Nervous and Mental Diseases
