期刊文献+

同步放化疗在局部晚期非小细胞肺癌中的应用 被引量:2

Application of chemoradiotherapy in local advanced non-small cell lung cancer
原文传递
导出
摘要 目的探讨同步放化疗在局部晚期非小细胞肺癌(LA-NSCLC)中应用的临床疗效及不良反应。方法选择2009年1月至2011年3月收治的53例不能手术的局部晚期非小细胞肺癌患者采用同步放化疗治疗,设为治疗组;另选择本院同期收治的LA-NSCLC患者48例为对照组,采用放射治疗,对比评价两组的临床疗效及不良反应。结果两组患者经治疗后治疗组总有效率为58.5%,对照组总有效率为41.7%,两组比较差异有显著性(P<0.05)。结论局部晚期非小细胞肺癌应用同步放化疗综合治疗,近、远期疗效优于单纯放疗的患者,不良反应患者能耐受,均能完成治疗。 Objective To investigate the clinical efficacy and adverse reactions of concurrent chemoradiotherapy in local advanced non-small cell lung cancer.Methods Our hospital from January 2009 to March 2011 treated 53 patients with inoperable local advanced non-small cell lung cancer treated with concurrent chemoradiation therapy as the treatment group;In our hospital over the same period of LA-NSCLC patients treated the control group 48 cases,the use of radiation therapy,were evaluated comparing the efficacy and adverse reactions.Results Two groups of patients after treatment total effective rate was 58.5%,in the control group the total effective rate was 41.7%,the difference was significant(P0.05).Conclusions Topical application of advanced non-small cell lung cancer concurrent radiotherapy and chemotherapy for the past,long-term efficacy is superior to radiotherapy alone,patients with adverse reactions can tolerate,be able to complete treatment.
出处 《医药论坛杂志》 2011年第24期20-21,24,共3页 Journal of Medical Forum
关键词 非小细胞肺癌 晚期 局部 Non-small cell lung cancer The late Local Concurrent radiotherapy and chemotherapy
  • 相关文献

参考文献5

二级参考文献35

  • 1李付海,石安辉,朱广迎.局部晚期非小细胞肺癌同步放化疗进展[J].中国肿瘤,2009,18(10):831-834. 被引量:11
  • 2张湘茹,孙燕.紫杉醇治疗非小细胞肺癌[J].中国新药杂志,1996,5(4):245-248. 被引量:31
  • 3廖开莲 肖华武 罗永忠 等.紫杉醇联合治疗28例晚期非小细胞肺癌临床观察.J Nail Cancer Inst,1992,84(24):58-58.
  • 4Reckeh B,Metre H,Pfluger K H,et al.Severe lymphocytopenia and interstitial pneumonia in patients treated with paclitaxel and simultaneous radiotherapy for non-small cell lung cance[J].J Clin Oncol,1996,14(6):1071-1076.
  • 5Resell R. The integration of newer agents into neoadjuvant therapy [ J ]. Semin Oncol, 1998,25 ( Suppl 8) :24.
  • 6Candara DR,Lara JP,Goldherg Z,et al. Neoadjuvant therapy for non - small cell lung cancer[ J ]. Anticancer Drugs ,2001,12 ( Suppl 1 ) : S5.
  • 7Gillman RO,Herdon J,Seagren SL,et al. Improved survival in stage Ⅲ non - small cell lung cancer: seven -year follow up of cancer leukemia group B (CALGB) 8433 trial[J]. J Natl Cancer Inst, 1996,88 (17) : 1210.
  • 8Marino P, Preatoni A, Cantoni A. Randomized trials of radiotherapy alone versus combined chemotherapy and radiotherapy in stages Ⅲa and Ⅲb non - small cell lung cancer. A meta - a- nalysis [ J ]. Cancer, 1995,76 ( 6 ) :593.
  • 9Fumse K,Fukuoka M,Kawahara M,et al. Phase Ⅲ study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresect - able stage Ⅲ non - small - cell lung cancer [ J ] . J Clin Oncol, 1999, 17 ( 15 ) :2692.
  • 10Curran D, Scott C, Langer C, et al. Long- term benefit is observed in a phase Ⅲ comparison of sequential vs. concurrent chemo - radiation for patients with unresected stage Ⅲ NSCLC: RTOG9410 [ J ]. Proc Am Soc Clin Oncol,2003,22 ( 13 ) :2499a.

共引文献28

同被引文献11

引证文献2

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部