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老年2型糖尿病合并骨质疏松症患者发病的相关因素分析 被引量:10

Correlation factor analysis in older type 2 diabetes patients with osteoporosis
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摘要 目的探讨老年2型糖尿病合并骨质疏松症患者发病的相关危险因素。方法对本院106例老年2型糖尿病合并骨质疏松症患者的年龄、体重指数(BMI)、糖尿病病程与其骨密度(BMD)进行相关因素分析。结果老年2型糖尿病合并骨质疏松症患者中,80岁组的腰椎[(0.756±0.099)g/cm^2]、股骨颈[(0.658±0.111)g/cm^2]及Wards三角[(0.525±0.064)g/cm^2]BMD值较60岁组[(0.883±0.112)g/cm^2、(0.781±0.130)g/cm^2、(0.6274±0.118)g/cm^2]明显下降(P〈0.05)。低体重组(BMI≤20kg/m^2)的腰椎[(0.738±O.114)g/cm^2)]、股骨颈[(0.664±O.112)g/cm^2)]BMD值较正常体重组[(0.816±0.138)g/cm^2、(0.727±0.134)g/cm^2]明显下降(P〈0.05)。糖尿病病程〉10年组的腰椎[(0.743±O.122)g/cm^2]、股骨颈[(0.719±0.147)g/cm^2]BMD值较病程〈5年组[(0.886±0.132)g/cm^2、(0.792±0.122)g/cm^2]明显下降(P〈0.05)。骨密度与年龄、糖尿病病程呈负相关(P〈0.05),与体重指数呈正相关(P〈0.05)。结论老年2型糖尿病合并骨质疏松症患者发病与高龄、低体重指数、糖尿病病程长的危险因素密切相关。 Objective To investigate the correlation factors in older type 2 diabetes patients with osteoporosis. Methods The related risk factors including their age, body mass index( BMI), history of dis- ease and bone mineral density( BMD)were analyzed in 106 older type 2 diabetes patients with osteoporosis, who were hospitalized in the first affiliated hospital of Guangzhou Medical College during January 2000 to December 2010. Results BMD of lumbar[ (0. 756 ± 0. 099)g/cm^2 ], neck of femur [ (0. 658 ± 0. 111 ) g/cm^2] and wards triangle[ (0. 525 ± 0. 064)g/cm^2] in the eighty group were distinctly reduced than the sixty group [ (0. 883 ± 0. 112) g/cm^2, (0. 781 ± 0. 130) g/cm2, ( 0. 627 ± 0. 118 ) g/cm^2] ( P 〈 0. 05 ). BMD of lumbar[ (0. 738 ± 0. 114) g/cm^2 ) ] and neck of femur [ ( 0. 664 ± 0. 112 ) g/cm2 ) ] in low weight patients (BMI≤20 kg/m2) were distinctly reduced than normal BMI group [ (0. 816±0. 138 )g/cm^2, (0. 727± 0. 134) g/cm^2 ] ( P 〈 0. 05 ). BMD of lumbar [ ( 0. 743 ± 0. 122 ) g/cm^2 ] and neck of femur [( 0. 719±0. 147) g/cm2 ] in patients with course of diabetes more than 10 years were distinctly reduced than the pa- tients with less course[ (0. 886±0. 132 ) g/cm^2, ( 0. 792 ± 0. 122 ) g/cm^2 ] ( P 〈 0. 05 ). BMD was nega- tively correlated with age and history of diabetes( P 〈 0. 05). BMD was positively correlated with BMI( P 〈 0. 05 ). Conclusions Older, low BMI and long history of diabetes are the risk factors of older type 2 di- abetes patients with osteoporosis.
作者 刘嘉眉
出处 《中国医师杂志》 CAS 2012年第1期31-33,共3页 Journal of Chinese Physician
关键词 糖尿病 2型/并发症/病因学 骨质疏松/并发症/病因学 危险因素 Diabetes mellitus, type 2/CO/ET Osteoporosis/CO/ET Risk factors
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  • 1刘丽萍.糖尿病合并骨质疏松症西医治疗探讨[J].现代养生,2013,0(18):18-18. 被引量:2
  • 2吴伏娜,米涌,钟紫茹.适宜钙饮食对老年男性骨质疏松的影响[J].武汉大学学报(医学版),2004,25(4):464-466. 被引量:4
  • 3皮银珍,廖二元,伍贤平,罗湘杭,张红,谢辉,曹行之.女性骨转换指标与年龄和腰椎骨密度的关系[J].中华内分泌代谢杂志,2005,21(5):441-445. 被引量:17
  • 4罗南萍,胡成进,孙晓明,王瑞山,白璐,刘恒国.老年骨质疏松患者血清瘦素水平与IGF-1等相关因素的研究[J].中国老年学杂志,2006,26(1):31-32. 被引量:14
  • 5中国健康促进基金会骨质疏松防治中国白皮书编委会.骨质疏松中国白皮书[J].中华健康管理学杂志,2009,3(3):148.
  • 6Ding KH ,Wang ZZ,Hamrich MW,et al.Disordered osteoclast for-mation in RAGE-deficient mouse establishes an essential role forRAGE in diabetes related bone loss [J].Biochem biophys ResCommon ,2006 ,340(4):1091-1097.
  • 7Heppner HJ, Jurgen M, Sieber BC, et al. Laboratory aspects relating to the detection and prevention of frailty [ J ]. Int J Prev Med, 2010, 1 : 149 - 157.
  • 8Takashi Ito, Stephen WS, Junichi A, et al. The potential usefulness of taurine on diabetes mellitus and its complications [ J 1. Amion Acids,2012,42:1529 - 1539.
  • 9Elsa ss, Jane AC. Diabetes mellitus, bone mineral density, and fracture risk[J]. Curr Opin Endoerinol Diabetes Obes,2008,14:429-435.
  • 10Kuchuk NO, Pluijm SM, vail Sehoor NM, et al. Relationships of ser-um 25 - hydroxyvitamin D to bone mineral density and serum para- thyroid hormone and markers of bone turnover in older persons E J ]- J Clin Endoerinol Metab,2009,94(4) :1244 -1250.

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